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Literature DB >> 24684382

Estrogen receptor mutations in breast cancer-an anticipated "rediscovery?".

Vincent Giguère¹.

Abstract

Entities: Disease Gene

Mesh：

Substances：
Receptors, Estrogen

Year: 2014 PMID： 24684382 PMCID： PMC5414921 DOI： 10.1210/me.2014-1071

Source DB: PubMed Journal: Mol Endocrinol ISSN： 0888-8809

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5 in total

1. An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer.

Authors: Q X Zhang; A Borg; D M Wolf; S Oesterreich; S A Fuqua
Journal: Cancer Res Date: 1997-04-01 Impact factor: 12.701

2. Ligand-independent activation of the estrogen receptors alpha and beta by mutations of a conserved tyrosine can be abolished by antiestrogens.

Authors: G B Tremblay; A Tremblay; F Labrie; V Giguère
Journal: Cancer Res Date: 1998-03-01 Impact factor: 12.701

3. Activating ESR1 mutations in hormone-resistant metastatic breast cancer.

Authors: Dan R Robinson; Yi-Mi Wu; Pankaj Vats; Fengyun Su; Robert J Lonigro; Xuhong Cao; Shanker Kalyana-Sundaram; Rui Wang; Yu Ning; Lynda Hodges; Amy Gursky; Javed Siddiqui; Scott A Tomlins; Sameek Roychowdhury; Kenneth J Pienta; Scott Y Kim; J Scott Roberts; James M Rae; Catherine H Van Poznak; Daniel F Hayes; Rashmi Chugh; Lakshmi P Kunju; Moshe Talpaz; Anne F Schott; Arul M Chinnaiyan
Journal: Nat Genet Date: 2013-11-03 Impact factor: 38.330

4. Comprehensive molecular portraits of human breast tumours.

Authors:
Journal: Nature Date: 2012-09-23 Impact factor: 49.962

5. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer.

Authors: Weiyi Toy; Yang Shen; Helen Won; Bradley Green; Rita A Sakr; Marie Will; Zhiqiang Li; Kinisha Gala; Sean Fanning; Tari A King; Clifford Hudis; David Chen; Tetiana Taran; Gabriel Hortobagyi; Geoffrey Greene; Michael Berger; José Baselga; Sarat Chandarlapaty
Journal: Nat Genet Date: 2013-11-03 Impact factor: 38.330

5 in total

3 in total

Estrogen receptor mutations in breast cancer-an anticipated "rediscovery?".

1. An estrogen receptor mutant with strong hormone-independent activity from a metastatic breast cancer.

2. Ligand-independent activation of the estrogen receptors alpha and beta by mutations of a conserved tyrosine can be abolished by antiestrogens.

3. Activating ESR1 mutations in hormone-resistant metastatic breast cancer.

4. Comprehensive molecular portraits of human breast tumours.

5. ESR1 ligand-binding domain mutations in hormone-resistant breast cancer.

Review 1. Metastatic breast cancer: The Odyssey of personalization.

2. ESR1 mutations affect anti-proliferative responses to tamoxifen through enhanced cross-talk with IGF signaling.

Review 3. The Impact of ESR1 Mutations on the Treatment of Metastatic Breast Cancer.