Nicola Logallo1, Halvor Naess2, Ulrike Waje-Andreassen3, Lars Thomassen4. 1. Center for Neurovascular Diseases, Haukeland University Hospital, Bergen, Norway. Electronic address: nicola.logallo@gmail.com. 2. Centre for Age-related Medicine, Stavanger University Hospital, Stavanger, Norway. 3. Center for Neurovascular Diseases, Haukeland University Hospital, Bergen, Norway. 4. Department of Clinical Medicine, University of Bergen, Bergen, Norway.
Abstract
BACKGROUND: There is no data about prevalence of intracranial stenosis (IS) in Northern Europe. This study aimed to investigate the prevalence of symptomatic and asymptomatic IS in a Norwegian, community-based ischemic stroke population. METHODS: In a prospective study, all ischemic stroke or transient ischemic attack (TIA) patients were screened for IS by transcranial color-coded sonography, magnetic resonance angiography, and/or computed tomography angiography. Patients with IS and any cardiac arrhythmia or other possible causes of IS than atherosclerosis were excluded. IS was defined as symptomatic if the infarct/symptoms were related to the territory of the stenotic artery. Risk factors for cerebrovascular disease were registered on admission. RESULTS: During an 18-month study period, 607 patients had an ischemic stroke or a TIA. Out of 69 patients with IS (11.4%), 7 patients were excluded because having atrial fibrillation, and IS of possible atherosclerotic etiology was therefore diagnosed in 62 patients (10.2%). IS was symptomatic in 45 patients (7.4%). Diabetes mellitus was the only risk factor significantly associated with symptomatic IS (odds ratio 2.39, 95% confidence interval [CI] 1.03-5.54, P=.04). CONCLUSIONS: IS occurs in approximately 10% and is symptomatic in about 7% of a Norwegian ischemic stroke/TIA population. Diabetes mellitus appears to be the major risk factor for IS.
BACKGROUND: There is no data about prevalence of intracranial stenosis (IS) in Northern Europe. This study aimed to investigate the prevalence of symptomatic and asymptomatic IS in a Norwegian, community-based ischemic stroke population. METHODS: In a prospective study, all ischemic stroke or transient ischemic attack (TIA) patients were screened for IS by transcranial color-coded sonography, magnetic resonance angiography, and/or computed tomography angiography. Patients with IS and any cardiac arrhythmia or other possible causes of IS than atherosclerosis were excluded. IS was defined as symptomatic if the infarct/symptoms were related to the territory of the stenotic artery. Risk factors for cerebrovascular disease were registered on admission. RESULTS: During an 18-month study period, 607 patients had an ischemic stroke or a TIA. Out of 69 patients with IS (11.4%), 7 patients were excluded because having atrial fibrillation, and IS of possible atherosclerotic etiology was therefore diagnosed in 62 patients (10.2%). IS was symptomatic in 45 patients (7.4%). Diabetes mellitus was the only risk factor significantly associated with symptomatic IS (odds ratio 2.39, 95% confidence interval [CI] 1.03-5.54, P=.04). CONCLUSIONS: IS occurs in approximately 10% and is symptomatic in about 7% of a Norwegian ischemic stroke/TIA population. Diabetes mellitus appears to be the major risk factor for IS.
Authors: Richard B Olatunji; Godwin I Ogbole; Omolola M Atalabi; Abiodun O Adeyinka; Ikeola Lagunju; Alexander Oyinlade; Olufunmilola Ogun; Mayowa O Owolabi; Oluremi A Ogunseyinde; Adesola Ogunniyi Journal: West Afr J Ultrasound Date: 2015
Authors: Robert Hurford; Frank J Wolters; Linxin Li; Kui Kai Lau; Wilhelm Küker; Peter M Rothwell Journal: JAMA Neurol Date: 2020-08-01 Impact factor: 18.302