Literature DB >> 24679102

Biofilm prevention on cochlear implants.

Yael Goldfinger, Michal Natan, Chaim N Sukenik, Ehud Banin, Jona Kronenberg.   

Abstract

OBJECTIVES: To examine the efficiency of a bacteria-resistant coating for the polydimethylsiloxane (PDMS) casing of cochlear implants.
METHODS: The coatings are based on thin titania films that are made by liquid phase deposition or atomic layer deposition. The antibacterial activity of the coating was tested by two different detection assays: BCA protein and confocal microscopy.
RESULTS: Coating the PDMS with thin films (10-40 nm) of titania significantly reduces the accumulation of bacteria. DISCUSSION: Thin oxide films made under conditions that do not undermine the integrity of polymeric materials can be used as anti-microbial coatings for soft polymers such as the PDMS that is used as a casing for cochlear implants or other medical devices.

Entities:  

Keywords:  Biofilm; Cochlear implant; Infection; PDMS; Titania

Mesh:

Substances:

Year:  2014        PMID: 24679102     DOI: 10.1179/1754762813Y.0000000061

Source DB:  PubMed          Journal:  Cochlear Implants Int        ISSN: 1467-0100


  1 in total

1.  Introducing a semi-coated model to investigate antibacterial effects of biocompatible polymers on titanium surfaces.

Authors:  Andreas Winkel; Wibke Dempwolf; Eva Gellermann; Magdalena Sluszniak; Sebastian Grade; Wieland Heuer; Michael Eisenburger; Henning Menzel; Meike Stiesch
Journal:  Int J Mol Sci       Date:  2015-02-17       Impact factor: 5.923

  1 in total

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