Jacqueline Costa Dias Pitangueira1, Luciana Rodrigues Silva2, Mônica Leila Portela de Santana3, Maria da Conceição Monteiro da Silva3, Priscila Ribas de Farias Costa4, Vânia D'Almeida5, Ana Marlúcia de Oliveira Assis6. 1. Professor. Center for Health Sciences. Federal University of Recôncavo of Bahia. Santo Antônio de Jesus. State of Bahia. Brazil.. jack_cdias@hotmail.com. 2. Professor PhD. School of Medicine of Bahia. Head of the Paediatric Gastroenterology and Hepatology Unity. Federal University of Bahia. Salvador. State of Bahia. Brazil.. 3. Professor PhD. School of Nutrition. Federal University of Bahia. Salvador, state of Bahia, Brazil.. 4. Professor. Center for Health Sciences. Federal University of Recôncavo of Bahia. Santo Antônio de Jesus. State of Bahia. Brazil.. 5. Professor PhD. Department of Psychobiology. Federal University of São Paulo. São Paulo. Brazil.. 6. Professor PhD. School of Nutrition. Federal University of Bahia. Salvador. State of Bahia. Brazil..
Abstract
BACKGROUND: the risk factors associated to metabolic syndrome (MS) have been extensively studied in adults, but in children and adolescents it is poorly explored. OBJECTIVE: To identify the prevalence of MS and associated factors in children and adolescents. METHODS: A cross-sectional study with 540 children and adolescents from 7 to 14 years of age. The socioeconomic, demographic and lifestyle data and the family history of chronic diseases were reported by the individual and/or guardian and recorded in a structured questionnaire. Biochemical tests (fasting blood glucose, triacylglycerols, reduced high-density lipoprotein, very-low-density lipoprotein, homocysteine and cysteine), an anthropometric assessment and a blood pressure measurement were performed. MS was defined according to the criteria of The National Cholesterol Education Program Adult Treatment Panel III adapted by Ferranti. A Poisson regression was used to identify the factors statistically associated with MS. RESULTS: The MS prevalence was 12.8%, in which the most frequent component was a decreased high-density lipoprotein level (58.2%), followed by hypertriglyceridemia (41.8%), elevated blood pressure (29.1%), increased waist circumference (26.7%) and hyperglycemia (7.2%). Associations between metabolic syndrome and overweight [prevalence ratio (PR): 2.2 (1.22-3.95)], father education [PR: 2.19 (1.10-4.37)], serum very low-density lipoprotein concentration [PR: 1.08 (1.04-1.11)] and concomitantly increased serum homocysteine and cysteine concentrations [PR: 2.58 (1.32-5.04)] were observed. CONCLUSIONS: The MS prevalence is high in children and adolescents and it is increased in patients with overweight, higher father education, increased serum very-low-density lipoprotein concentrations and a concomitant serum homocysteine and cysteine high levels. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.
BACKGROUND: the risk factors associated to metabolic syndrome (MS) have been extensively studied in adults, but in children and adolescents it is poorly explored. OBJECTIVE: To identify the prevalence of MS and associated factors in children and adolescents. METHODS: A cross-sectional study with 540 children and adolescents from 7 to 14 years of age. The socioeconomic, demographic and lifestyle data and the family history of chronic diseases were reported by the individual and/or guardian and recorded in a structured questionnaire. Biochemical tests (fasting blood glucose, triacylglycerols, reduced high-density lipoprotein, very-low-density lipoprotein, homocysteine and cysteine), an anthropometric assessment and a blood pressure measurement were performed. MS was defined according to the criteria of The National Cholesterol Education Program Adult Treatment Panel III adapted by Ferranti. A Poisson regression was used to identify the factors statistically associated with MS. RESULTS: The MS prevalence was 12.8%, in which the most frequent component was a decreased high-density lipoprotein level (58.2%), followed by hypertriglyceridemia (41.8%), elevated blood pressure (29.1%), increased waist circumference (26.7%) and hyperglycemia (7.2%). Associations between metabolic syndrome and overweight [prevalence ratio (PR): 2.2 (1.22-3.95)], father education [PR: 2.19 (1.10-4.37)], serum very low-density lipoprotein concentration [PR: 1.08 (1.04-1.11)] and concomitantly increased serum homocysteine and cysteine concentrations [PR: 2.58 (1.32-5.04)] were observed. CONCLUSIONS: The MS prevalence is high in children and adolescents and it is increased in patients with overweight, higher father education, increased serum very-low-density lipoprotein concentrations and a concomitant serum homocysteine and cysteine high levels. Copyright AULA MEDICA EDICIONES 2014. Published by AULA MEDICA. All rights reserved.