Literature DB >> 24677423

Drug delivery with PEGylated MoS2 nano-sheets for combined photothermal and chemotherapy of cancer.

Teng Liu1, Chao Wang, Xing Gu, Hua Gong, Liang Cheng, Xiaoze Shi, Liangzhu Feng, Baoquan Sun, Zhuang Liu.   

Abstract

MoS2 nanosheets functionalized with poly-ethylene glycol are for the first time used as a multifunctional drug delivery system with high drug loading capacities. Using doxorubicin as the model drug and taking advantages of the strong near-infrared absorbance of MoS2, combined photothermal and chemotherapy of cancer is realized in animal experiments, achieving excellent synergistic anti-tumor effect upon systemic administration.
© 2014 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  2D nanostructure; MoS2 nanosheet; combination therapy; drug delivery; photothermal therapy

Mesh：

Substances：

Year:  2014        PMID： 24677423     DOI： 10.1002/adma.201305256

Source DB:  PubMed          Journal:  Adv Mater        ISSN： 0935-9648            Impact factor:   30.849


  107 in total

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