Literature DB >> 24677234

Personal reflections on big science, small science, or the right mix.

Michael S Lauer1.   

Abstract

Entities:  

Keywords:  National Heart, Lung, and Blood Institute; biomedical research; economics

Mesh：

Year:  2014        PMID： 24677234      PMCID： PMC4006109          DOI： 10.1161/CIRCRESAHA.114.303627

Source DB:  PubMed          Journal:  Circ Res        ISSN： 0009-7330            Impact factor:   17.367


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  12 in total

1.  Big, small or mezzo? Lessons from science studies for the ongoing debate about 'big' versus 'little' research projects.

Authors:  Niki Vermeulen; John N Parker; Bart Penders
Journal:  EMBO Rep       Date:  2010-05-14       Impact factor: 8.807

2.  Presidential address. What's so special about science (and how much should we spend on it?).

Authors:  William H Press
Journal:  Science       Date:  2013-11-15       Impact factor: 47.728

3.  The end of "small science"?

Authors:  Bruce Alberts
Journal:  Science       Date:  2012-09-28       Impact factor: 47.728

4.  A threat to medical innovation.

Authors:  Michael Rosbash
Journal:  Science       Date:  2011-07-08       Impact factor: 47.728

5.  History of science. A golden era of Nobel laureates.

Authors:  Joseph L Goldstein; Michael S Brown
Journal:  Science       Date:  2012-11-23       Impact factor: 47.728

6.  On the value of portfolio diversity in heart, lung, and blood research.

Authors:  Zorina S Galis; W Keith Hoots; James P Kiley; Michael S Lauer
Journal:  Am J Respir Crit Care Med       Date:  2012-10-01       Impact factor: 21.405

7.  Enabling scientific innovation.

Authors:  James S Langer
Journal:  Science       Date:  2012-10-12       Impact factor: 47.728

8.  The Women's Health Initiative--a victory for women and their health.

Authors:  Elizabeth G Nabel
Journal:  JAMA       Date:  2013-10-02       Impact factor: 56.272

9.  Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.

Authors:  Benjamin F Voight; Gina M Peloso; Marju Orho-Melander; Ruth Frikke-Schmidt; Maja Barbalic; Majken K Jensen; George Hindy; Hilma Hólm; Eric L Ding; Toby Johnson; Heribert Schunkert; Nilesh J Samani; Robert Clarke; Jemma C Hopewell; John F Thompson; Mingyao Li; Gudmar Thorleifsson; Christopher Newton-Cheh; Kiran Musunuru; James P Pirruccello; Danish Saleheen; Li Chen; Alexandre F R Stewart; Arne Schillert; Unnur Thorsteinsdottir; Gudmundur Thorgeirsson; Sonia Anand; James C Engert; Thomas Morgan; John Spertus; Monika Stoll; Klaus Berger; Nicola Martinelli; Domenico Girelli; Pascal P McKeown; Christopher C Patterson; Stephen E Epstein; Joseph Devaney; Mary-Susan Burnett; Vincent Mooser; Samuli Ripatti; Ida Surakka; Markku S Nieminen; Juha Sinisalo; Marja-Liisa Lokki; Markus Perola; Aki Havulinna; Ulf de Faire; Bruna Gigante; Erik Ingelsson; Tanja Zeller; Philipp Wild; Paul I W de Bakker; Olaf H Klungel; Anke-Hilse Maitland-van der Zee; Bas J M Peters; Anthonius de Boer; Diederick E Grobbee; Pieter W Kamphuisen; Vera H M Deneer; Clara C Elbers; N Charlotte Onland-Moret; Marten H Hofker; Cisca Wijmenga; W M Monique Verschuren; Jolanda M A Boer; Yvonne T van der Schouw; Asif Rasheed; Philippe Frossard; Serkalem Demissie; Cristen Willer; Ron Do; Jose M Ordovas; Gonçalo R Abecasis; Michael Boehnke; Karen L Mohlke; Mark J Daly; Candace Guiducci; Noël P Burtt; Aarti Surti; Elena Gonzalez; Shaun Purcell; Stacey Gabriel; Jaume Marrugat; John Peden; Jeanette Erdmann; Patrick Diemert; Christina Willenborg; Inke R König; Marcus Fischer; Christian Hengstenberg; Andreas Ziegler; Ian Buysschaert; Diether Lambrechts; Frans Van de Werf; Keith A Fox; Nour Eddine El Mokhtari; Diana Rubin; Jürgen Schrezenmeir; Stefan Schreiber; Arne Schäfer; John Danesh; Stefan Blankenberg; Robert Roberts; Ruth McPherson; Hugh Watkins; Alistair S Hall; Kim Overvad; Eric Rimm; Eric Boerwinkle; Anne Tybjaerg-Hansen; L Adrienne Cupples; Muredach P Reilly; Olle Melander; Pier M Mannucci; Diego Ardissino; David Siscovick; Roberto Elosua; Kari Stefansson; Christopher J O'Donnell; Veikko Salomaa; Daniel J Rader; Leena Peltonen; Stephen M Schwartz; David Altshuler; Sekar Kathiresan
Journal:  Lancet       Date:  2012-05-17       Impact factor: 79.321

10.  Big Science vs. Little Science: How Scientific Impact Scales with Funding.

Authors:  Jean-Michel Fortin; David J Currie
Journal:  PLoS One       Date:  2013-06-19       Impact factor: 3.240
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  6 in total

1.  Matching taxpayer funding to population health needs: not so simple.

Authors:  Michael S Lauer; David Gordon; Michelle Olive
Journal:  Circ Res       Date:  2015-04-10       Impact factor: 17.367

2.  Future of fundamental discovery in US biomedical research.

Authors:  Michael Levitt; Jonathan M Levitt
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-05       Impact factor: 11.205

3.  What can we do about exploratory analyses in clinical trials?

Authors:  Lem Moyé
Journal:  Contemp Clin Trials       Date:  2015-09-25       Impact factor: 2.226

4.  Maximizing the return on taxpayers' investments in fundamental biomedical research.

Authors:  Jon R Lorsch
Journal:  Mol Biol Cell       Date:  2015-05-01       Impact factor: 4.138

5.  The validation of peer review through research impact measures and the implications for funding strategies.

Authors:  Stephen A Gallo; Afton S Carpenter; David Irwin; Caitlin D McPartland; Joseph Travis; Sofie Reynders; Lisa A Thompson; Scott R Glisson
Journal:  PLoS One       Date:  2014-09-03       Impact factor: 3.240

6.  Funding of Hispanic/Latino Health-Related Research by the National Institutes of Health: An Analysis of the Portfolio of Research Program Grants on Six Health Topic Areas.

Authors:  M Larissa Avilés-Santa; Laura Hsu; Tram Kim Lam; S Sonia Arteaga; Ligia Artiles; Sean Coady; Lawton S Cooper; Jennifer Curry; Patrice Desvigne-Nickens; Holly L Nicastro; Adelaida Rosario
Journal:  Front Public Health       Date:  2020-08-28
  6 in total

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