BACKGROUND AND PURPOSE: It remains uncertain if impaired glucose regulation (IGR) as a predictor for stroke outcomes. This study aimed at observing the effect of IGR on the 1-year outcomes in Chinese patients with ischemic stroke. METHODS: Patients with acute ischemic stroke were recruited consecutively in multihospitals across China. Oral glucose tolerance test was performed to identify IGR. Cox proportion hazard model was performed to investigate the effect of IGR on 1-year mortality or stroke recurrence in patients with ischemic stroke. RESULTS: The study recruited 2639 patients with ischemic stroke. IGR was shown as an independent risk factor for the mortality of patients with ischemic stroke (hazard ratio [95% confidence interval], 3.088 [1.386-6.884]; P=0.006). However, IGR showed no significant effects on the dependency or stroke recurrence of patients (P=0.540 and 0.618, respectively). CONCLUSIONS: IGR was an independent predictor for the mortality of patients with ischemic stroke. IGR should be highlighted and intervened actively in the patients with ischemic stroke.
BACKGROUND AND PURPOSE: It remains uncertain if impaired glucose regulation (IGR) as a predictor for stroke outcomes. This study aimed at observing the effect of IGR on the 1-year outcomes in Chinese patients with ischemic stroke. METHODS:Patients with acute ischemic stroke were recruited consecutively in multihospitals across China. Oral glucose tolerance test was performed to identify IGR. Cox proportion hazard model was performed to investigate the effect of IGR on 1-year mortality or stroke recurrence in patients with ischemic stroke. RESULTS: The study recruited 2639 patients with ischemic stroke. IGR was shown as an independent risk factor for the mortality of patients with ischemic stroke (hazard ratio [95% confidence interval], 3.088 [1.386-6.884]; P=0.006). However, IGR showed no significant effects on the dependency or stroke recurrence of patients (P=0.540 and 0.618, respectively). CONCLUSIONS: IGR was an independent predictor for the mortality of patients with ischemic stroke. IGR should be highlighted and intervened actively in the patients with ischemic stroke.
Authors: Daniela Frizon Alfieri; Marcio Francisco Lehmann; Tamires Flauzino; Maria Caroline Martins de Araújo; Nicolas Pivoto; Rafaele Maria Tirolla; Andrea Name Colado Simão; Michael Maes; Edna Maria Vissoci Reiche Journal: Neurotox Res Date: 2020-05-15 Impact factor: 3.911
Authors: Michael J Haley; Siddharth Krishnan; David Burrows; Leon de Hoog; Jamie Thakrar; Ingo Schiessl; Stuart M Allan; Catherine B Lawrence Journal: J Cereb Blood Flow Metab Date: 2017-11-24 Impact factor: 6.200
Authors: Sang-Hwa Lee; Min Uk Jang; Yerim Kim; So Young Park; Chulho Kim; Yeo Jin Kim; Jong-Hee Sohn Journal: Front Endocrinol (Lausanne) Date: 2020-04-21 Impact factor: 5.555