Literature DB >> 24674580

Preservation of the internal vesical sphincter and proximal urethra during retropubic radical prostatectomy may improve earlier recovery of continence in selected patients.

E Brunocilla1, R Schiavina1, M Borghesi2, C Pultrone1, V Vagnoni1, M S Rossi1, M Cevenini1, L Bianchi1, E Molinaroli1, G Gentile1, G Martorana1.   

Abstract

OBJECTIVES: To evaluate the influence of preservation of the muscular internal sphincter and proximal urethra on continence recovery after radical prostatectomy (RP).
MATERIAL AND METHODS: Fifty-five consecutive patients with organ confined prostate cancer were submitted to RP with the preservation of muscular internal sphincter and the proximal urethra (group 1) and compared to 55 patients submitted to standard procedure (group 2). Continence rates were assessed using a self-administrated questionnaire at 3, 7, 30 days and 3, 12 months after removal of the catheter.
RESULTS: Group 1 had a faster recovery of continence than group 2 at 3 days (50.9% vs. 25.5%; P=.005), at 7 days (78.2% vs. 58.2%; P=.020), at 30 days (80.0% vs. 61.8%; P=.029) and at 3 months (81.8% vs. 61.8%; P=.017); there were no statistically difference in terms of continence at 12 months among the two groups. Multivariate logistic regression analysis of continence showed that surgical technique was significantly associated with earlier time to continence at 3 and 7 days. The two groups had no significant differences in terms of surgical margins.
CONCLUSIONS: Our modified technique of RP with preservation of smooth muscular internal sphincter as well as of the proximal urethra during bladder neck dissection resulted in significant increased early urinary continence at 3, 7, 30 days and 3 months after catheter removal. The technique does not increase the rate of positive margins and the duration of the procedure.
Copyright © 2013 AEU. Published by Elsevier Espana. All rights reserved.

Entities:  

Keywords:  Continencia urinaria; Cáncer de próstata; Esfínter urinario; Prostate cancer; Prostatectomía radical; Radical prostatectomy; Urethra; Uretra; Urinary continence; Urinary sphincter

Mesh:

Year:  2014        PMID: 24674580     DOI: 10.1016/j.acuro.2013.12.010

Source DB:  PubMed          Journal:  Actas Urol Esp        ISSN: 0210-4806            Impact factor:   0.994


  2 in total

Review 1.  Bladder neck preservation improves time to continence after radical prostatectomy: a systematic review and meta-analysis.

Authors:  Xueyou Ma; Kun Tang; Chunguang Yang; Guanqing Wu; Nan Xu; Meng Wang; Xing Zeng; Zhiquan Hu; Ranran Song; Bertram Yuh; Zhihua Wang; Zhangqun Ye
Journal:  Oncotarget       Date:  2016-10-11

2.  Holmium laser enucleation of prostate by using en-bloc and bladder neck preservation technique: technical consideration and influence on functional outcomes.

Authors:  Pu Li; Chengming Wang; Min Tang; Peng Han; Xiaoxin Meng
Journal:  Transl Androl Urol       Date:  2021-01
  2 in total

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