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Literature DB >> 24674102

Long term use of metformin leading to vitamin B 12 deficiency.

Abstract

Metformin is a commonly used oral hypoglycaemic agent worldwide. Gastrointestinal side effects and lactic acidosis related to metformin usage are commonly recognized. However, the associated vitamin B12 deficiency is less well known. We present a case of long term metformin use resulting in vitamin B12 deficiency.

Entities: Chemical Disease Gene

Keywords: Metformin; Pancytopaenia; Vitamin B12 deficiency

Mesh：

Substances：

Year: 2014 PMID： 24674102 DOI： 10.1016/j.diabres.2013.12.054

Source DB: PubMed Journal: Diabetes Res Clin Pract ISSN： 0168-8227 Impact factor: 5.602

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Cited

4 in total

1. Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.

Authors: Vanita R Aroda; Sharon L Edelstein; Ronald B Goldberg; William C Knowler; Santica M Marcovina; Trevor J Orchard; George A Bray; David S Schade; Marinella G Temprosa; Neil H White; Jill P Crandall
Journal: J Clin Endocrinol Metab Date: 2016-02-22 Impact factor: 5.958

Long term use of metformin leading to vitamin B 12 deficiency.

1. Long-term Metformin Use and Vitamin B12 Deficiency in the Diabetes Prevention Program Outcomes Study.

2. The effect of metformin on vitamin B12 level in pediatric patients.

3. Vitamin B12 deficiency: an important reversible co-morbidity in neuropsychiatric manifestations.

4. Metformin toxicity: A meta-summary of case reports.