Literature DB >> 24670991

Emerging pathways in the regulation of whole body cholesterol flux: therapeutic opportunities to target atherosclerosis?

Rabban Mangat1, Spencer D Proctor.   

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Year:  2014        PMID： 24670991      PMCID： PMC3995456          DOI： 10.1194/jlr.E049502

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


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  13 in total

1.  Simvastatin treatment upregulates intestinal lipid secretion pathways in a rodent model of the metabolic syndrome.

Authors:  Faye Borthwick; Rabban Mangat; Samantha Warnakula; Miriam Jacome-Sosa; Donna F Vine; Spencer D Proctor
Journal:  Atherosclerosis       Date:  2013-11-13       Impact factor: 5.162

2.  Trans-intestinal cholesterol efflux is not mediated through high density lipoprotein.

Authors:  Carlos L J Vrins; Roelof Ottenhoff; Karin van den Oever; Dirk R de Waart; J Kar Kruyt; Ying Zhao; Theo J C van Berkel; Louis M Havekes; Johannes M Aerts; Miranda van Eck; Patrick C N Rensen; Albert K Groen
Journal:  J Lipid Res       Date:  2012-07-16       Impact factor: 5.922

3.  Atorvastatin increases intestinal expression of NPC1L1 in hyperlipidemic men.

Authors:  André J Tremblay; Benoît Lamarche; Valéry Lemelin; Lizbeth Hoos; Suzanne Benjannet; Nabil G Seidah; Harry R Davis; Patrick Couture
Journal:  J Lipid Res       Date:  2010-12-01       Impact factor: 5.922

4.  JTT-130, a novel intestine-specific inhibitor of microsomal triglyceride transfer protein, ameliorates impaired glucose and lipid metabolism in Zucker diabetic fatty rats.

Authors:  T Hata; Y Mera; T Kawai; Y Ishii; Y Kuroki; K Kakimoto; T Ohta; M Kakutani
Journal:  Diabetes Obes Metab       Date:  2011-07       Impact factor: 6.577

5.  Inhibition of intestinal cholesterol absorption by ezetimibe in humans.

Authors:  Thomas Sudhop; Dieter Lütjohann; Annette Kodal; Michael Igel; Diane L Tribble; Sukrut Shah; Inna Perevozskaya; Klaus von Bergmann
Journal:  Circulation       Date:  2002-10-08       Impact factor: 29.690

6.  Lymphatic vasculature mediates macrophage reverse cholesterol transport in mice.

Authors:  Catherine Martel; Wenjun Li; Brian Fulp; Andrew M Platt; Emmanuel L Gautier; Marit Westerterp; Robert Bittman; Alan R Tall; Shu-Hsia Chen; Michael J Thomas; Daniel Kreisel; Melody A Swartz; Mary G Sorci-Thomas; Gwendalyn J Randolph
Journal:  J Clin Invest       Date:  2013-03-25       Impact factor: 14.808

Review 7.  Microsomal transfer protein inhibition in humans.

Authors:  Marina Cuchel; Daniel J Rader
Journal:  Curr Opin Lipidol       Date:  2013-06       Impact factor: 4.776

8.  Efficacy and safety of a microsomal triglyceride transfer protein inhibitor in patients with homozygous familial hypercholesterolaemia: a single-arm, open-label, phase 3 study.

Authors:  Marina Cuchel; Emma A Meagher; Hendrik du Toit Theron; Dirk J Blom; A David Marais; Robert A Hegele; Maurizio R Averna; Cesare R Sirtori; Prediman K Shah; Daniel Gaudet; Claudia Stefanutti; Giovanni B Vigna; Anna M E Du Plessis; Kathleen J Propert; William J Sasiela; LeAnne T Bloedon; Daniel J Rader
Journal:  Lancet       Date:  2012-11-02       Impact factor: 79.321

9.  Lymphatic vessels are essential for the removal of cholesterol from peripheral tissues by SR-BI-mediated transport of HDL.

Authors:  Hwee Ying Lim; Chung Hwee Thiam; Kim Pin Yeo; Radjesh Bisoendial; Chung Shii Hii; Kristine C Y McGrath; Kar Wai Tan; Alison Heather; J Steven Jonathan Alexander; Veronique Angeli
Journal:  Cell Metab       Date:  2013-05-07       Impact factor: 27.287

10.  Multiple functions of microsomal triglyceride transfer protein.

Authors:  M Mahmood Hussain; Paul Rava; Meghan Walsh; Muhammad Rana; Jahangir Iqbal
Journal:  Nutr Metab (Lond)       Date:  2012-02-21       Impact factor: 4.169
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  1 in total

Review 1.  Mechanisms of Comorbidities Associated With the Metabolic Syndrome: Insights from the JCR:LA-cp Corpulent Rat Strain.

Authors:  Abdoulaye Diane; W David Pierce; Sandra E Kelly; Sharon Sokolik; Faye Borthwick; Miriam Jacome-Sosa; Rabban Mangat; Jesus Miguel Pradillo; Stuart McRae Allan; Megan R Ruth; Catherine J Field; Rebecca Hutcheson; Petra Rocic; James C Russell; Donna F Vine; Spencer D Proctor
Journal:  Front Nutr       Date:  2016-10-10
  1 in total

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