Literature DB >> 2467045

Diagnostic value of immunoreactive phospholipase A2 in acute pancreatitis.

P Malfertheiner1, T Nevalainen, W Uhl, H Schädlich, M Büchler.   

Abstract

In a prospective clinical trial 85 patients with acute pancreatitis were analysed for serum total amylase, pancreatic amylase, pancreatic lipase, trypsin, elastase 1, and immunoreactive phospholipase A2 (IR-PLA2). The diagnostic sensitivity of serum IR-PLA2 was comparable to that of serum total amylase, pancreatic amylase, and trypsin. The specificity of IR-PLA2 is superior to that of serum total amylase determination due to the fact that the IR-PLA2 determination is based on an antibody against human pancreatic PLA2.

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Year:  1989        PMID: 2467045     DOI: 10.1007/bf01711350

Source DB:  PubMed          Journal:  Klin Wochenschr        ISSN: 0023-2173


  5 in total

1.  Serum elastase 1 in inflammatory pancreatic and gastrointestinal diseases and in renal insufficiency. A comparison with other serum pancreatic enzymes.

Authors:  P Malfertheiner; M Büchler; A Stanescu; W Uhl; H Ditschuneit
Journal:  Int J Pancreatol       Date:  1987-06

Review 2.  Hyperamylasemia: interpretation and newer approaches to evaluation.

Authors:  J E Berk; L Fridhandler
Journal:  Adv Intern Med       Date:  1980

Review 3.  Amylase--its clinical significance: a review of the literature.

Authors:  W B Salt; S Schenker
Journal:  Medicine (Baltimore)       Date:  1976-07       Impact factor: 1.889

4.  Time-resolved fluoroimmunoassay of human pancreatic phospholipase A2.

Authors:  J U Eskola; T J Nevalainen; T N Lövgren
Journal:  Clin Chem       Date:  1983-10       Impact factor: 8.327

5.  Diagnostic and prognostic value of serum elastase 1 in acute pancreatitis.

Authors:  M Büchler; P Malfertheiner; W Uhl; H G Beger
Journal:  Klin Wochenschr       Date:  1986-11-17
  5 in total
  3 in total

Review 1.  Serum amylase and lipase and urinary trypsinogen and amylase for diagnosis of acute pancreatitis.

Authors:  Gianluca Rompianesi; Angus Hann; Oluyemi Komolafe; Stephen P Pereira; Brian R Davidson; Kurinchi Selvan Gurusamy
Journal:  Cochrane Database Syst Rev       Date:  2017-04-21

2.  Urinary phospholipase A2 excretion in chronic pancreatic diseases.

Authors:  C Fabris; D Basso; M P Panozzo; G Del Favero; T Meggiato; M Plebani; C Ferrara; P Fogar; M Zaninotto; R Naccarato
Journal:  Int J Pancreatol       Date:  1992-06

3.  Prognostic value of serum phospholipase A in acute pancreatitis.

Authors:  M Büchler; P Malfertheiner; H Schädlich; T Nevalainen; T Mavromatis; H G Beger
Journal:  Klin Wochenschr       Date:  1989-02-01
  3 in total

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