Literature DB >> 24670137

Screening of Caatinga plants as sources of lectins and trypsin inhibitors.

José Hélton Vasconcelos Arcoverde1, Aline de Souza Carvalho, Fernanda Pacífico de Almeida Neves, Bianca Paiva Dionízio, Emmanuel Viana Pontual, Patrícia Maria Guedes Paiva, Thiago Henrique Napoleão, Maria Tereza dos Santos Correia, Márcia Vanusa da Silva, Maria das Graças Carneiro-da-Cunha.   

Abstract

Although it is one of the most threatened areas in the Earth, there are few studies on the biotechnological potential of the Caatinga. This work evaluated 36 extracts from 27 Caatinga plants for lectin and trypsin inhibitor activities. The presence of lectin was detected in 77.7% of samples by haemagglutinating assay. The highest values of specific haemagglutinating activity were found in extracts of leaves from Mimosa lewesii, Bauhinia acuruana and Manilkara rufula and in branches from Myracrodruon urundeuva. Trypsin inhibitor activity was detected in 63.9% of the tested extracts, strong inhibitory effect (>70%) being found in 11 samples. This work demonstrates that Caatinga is a potential source of bioactive plant proteins that can be isolated and studied for several applications. The biochemical prospecting of Caatinga is essential for collection of bioactive principles so as to add conservation value to the region.

Entities:  

Keywords:  Caatinga; biochemical prospecting; lectin; plant proteins; protease inhibitor

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Year:  2014        PMID: 24670137     DOI: 10.1080/14786419.2014.900497

Source DB:  PubMed          Journal:  Nat Prod Res        ISSN: 1478-6419            Impact factor:   2.861


  2 in total

1.  Streptomyces spp. Isolated from Marine and Caatinga Biomes in Brazil for the Biological Control of Duponchelia fovealis.

Authors:  Mariana Vieira Porsani; Carolina Gracia Poitevin; Sabina Moser Tralamazza; Mireli Trombin de Souza; Michele Trombin de Souza; Éder David Borges da Silva; Maria Aparecida Cassilha Zawadneak; Ida Chapaval Pimentel; Itamar Soares de Melo
Journal:  Neotrop Entomol       Date:  2022-01-12       Impact factor: 1.434

2.  Trichomonicidal and parasite membrane damaging activity of bidesmosic saponins from Manilkara rufula.

Authors:  Patrícia de Brum Vieira; Nícolas Luiz Feijó Silva; Camila Braz Menezes; Márcia Vanusa da Silva; Denise Brentan Silva; Norberto Peporine Lopes; Alexandre José Macedo; Jaume Bastida; Tiana Tasca
Journal:  PLoS One       Date:  2017-11-30       Impact factor: 3.240

  2 in total

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