Literature DB >> 24669887

Efficient synthesis of functionalized benzo[b][1,8]naphthyridine derivatives via three-component reaction catalyzed by L-proline.

Lei Fu1, Wei Lin, Ming-Hua Hu, Xue-Cheng Liu, Zhi-Bin Huang, Da-Qing Shi.   

Abstract

A facile and efficient one-pot procedure for the preparation of functionalized benzo[b][1,8]naphthyridine derivatives by three-component reaction of 2-chloroquinoline-3-carbaldehyde, 1,3-dicarbonyl compounds, and enaminones catalyzed by l-proline is described. This new protocol has the advantages of environmental friendliness, good yields, and convenient operation.

Entities:  

Keywords:  benzo[b][1,8]naphthyridine; l-proline; three-component reaction

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Substances：

Year:  2014        PMID： 24669887     DOI： 10.1021/co4001524

Source DB:  PubMed          Journal:  ACS Comb Sci        ISSN： 2156-8944            Impact factor:   3.784


  2 in total

1.  The regioselective one-pot four-component synthesis of novel functionalized 4H-pyrano[2, 3-b]quinoline derivatives using DABCO as a homogeneous organocatalyst.

Authors:  Masumeh Heydari; Ali Asghar Mohammadi; Mohammadreza Mosleh
Journal:  Mol Divers       Date:  2022-09-07       Impact factor: 3.364

Review 2.  Recent advances in the chemistry of 2-chloroquinoline-3-carbaldehyde and related analogs.

Authors:  Wafaa S Hamama; Mona E Ibrahim; Ayaa A Gooda; Hanafi H Zoorob
Journal:  RSC Adv       Date:  2018-02-23       Impact factor: 4.036
  2 in total

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