| Literature DB >> 24665047 |
Ngoc D B Le1, Yuqing Xing1, Chang Soo Kim1, Bo Yan1, Gulen Yesilbag Tonga1, Chaekyu Kim1, Richard W Vachet1, Vincent M Rotello1.
Abstract
Getting out is just as important for nano-therapeutics as getting in. Exocytosis rates determine residency time in the cell, an important determinant for therapeutic efficacy and also for eventual clearance from the cell. In this study, it is shown that exocytosis efficiency is determined by surface functionality, providing a strategy for optimizing nanocarriers.Entities:
Keywords: exocytosis; gold nanoparticle; inductively coupled plasma mass spectrometry; surface functionality
Mesh:
Substances:
Year: 2014 PMID: 24665047 PMCID: PMC4134693 DOI: 10.1002/adhm.201400001
Source DB: PubMed Journal: Adv Healthc Mater ISSN: 2192-2640 Impact factor: 9.933