Literature DB >> 24661858

Enantioseparation of chiral pharmaceuticals in biomedical and environmental analyses by liquid chromatography: an overview.

Ana R Ribeiro1, Alexandra S Maia2, Quezia B Cass3, Maria E Tiritan4.   

Abstract

This review aims to present the issues associated to enantioseparation of chiral pharmaceuticals in biological and environmental matrices using chiral stationary phases (CSP). Thus, it related some enantioselective methods in liquid chromatography (LC) and compares the importance given to chiral separation in biomedical and environmental fields. For that the most used CSP, the enantioselective chromatographic methods, their advantages and drawbacks were swiftly revised and compared. The recent advances and the limitations of chiral analytical methods in LC were also discussed.
Copyright © 2014 Elsevier B.V. All rights reserved.

Keywords:  Biological matrices; Chiral pharmaceuticals; Chiral stationary phases; Enantioselective chromatography; Environmental matrices

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Substances：

Year:  2014        PMID： 24661858     DOI： 10.1016/j.jchromb.2014.02.049

Source DB:  PubMed          Journal:  J Chromatogr B Analyt Technol Biomed Life Sci        ISSN： 1570-0232            Impact factor:   3.205


  8 in total

1.  Enantioselective analysis and degradation of isofenphos-methyl in vegetables by liquid chromatography-tandem mass spectrometry.

Authors:  Lidong Wang; Xiangyun Wang; Shanshan Di; Peipei Qi; Yuhan Sun; Xuewei Yang; Changshan Zhao; Xinquan Wang
Journal:  Environ Sci Pollut Res Int       Date:  2018-04-30       Impact factor: 4.223

Review 2.  Enantioselectivity in Drug Pharmacokinetics and Toxicity: Pharmacological Relevance and Analytical Methods.

Authors:  Maria Miguel Coelho; Carla Fernandes; Fernando Remião; Maria Elizabeth Tiritan
Journal:  Molecules       Date:  2021-05-23       Impact factor: 4.411

3.  Applicability of the Rayleigh equation for enantioselective metabolism of chiral xenobiotics by microsomes, hepatocytes and in-vivo retention in rabbit tissues.

Authors:  Shifra Jammer; Faina Gelman; Ovadia Lev
Journal:  Sci Rep       Date:  2016-03-29       Impact factor: 4.379

4.  StreptomeDB 2.0--an extended resource of natural products produced by streptomycetes.

Authors:  Dennis Klementz; Kersten Döring; Xavier Lucas; Kiran K Telukunta; Anika Erxleben; Denise Deubel; Astrid Erber; Irene Santillana; Oliver S Thomas; Andreas Bechthold; Stefan Günther
Journal:  Nucleic Acids Res       Date:  2015-11-28       Impact factor: 16.971

Review 5.  Enantiomeric Mixtures in Natural Product Chemistry: Separation and Absolute Configuration Assignment.

Authors:  Andrea N L Batista; Fernando M Dos Santos; João M Batista; Quezia B Cass
Journal:  Molecules       Date:  2018-02-23       Impact factor: 4.411

Review 6.  Chiral Drug Analysis in Forensic Chemistry: An Overview.

Authors:  Cláudia Ribeiro; Cristiana Santos; Valter Gonçalves; Ana Ramos; Carlos Afonso; Maria Elizabeth Tiritan
Journal:  Molecules       Date:  2018-01-28       Impact factor: 4.411

7.  Simultaneous Determination of Selegiline, Desmethylselegiline, R/S-methamphetamine, and R/S-amphetamine on Dried Urine Spots by LC/MS/MS: Application to a Pharmacokinetic Study in Urine.

Authors:  Lizhu Chen; Yingjia Yu; Gengli Duan; Xin Wang; Baohua Shen; Ping Xiang
Journal:  Front Chem       Date:  2019-04-17       Impact factor: 5.221

8.  Bovine serum albumin adsorbed on eremomycin and grafted on silica as new mixed-binary chiral sorbent for improved enantioseparation of drugs.

Authors:  Irina A Fedorova; Elena N Shapovalova; Oleg A Shpigun; Sergey M Staroverov
Journal:  J Food Drug Anal       Date:  2016-06-16       Impact factor: 6.157
  8 in total

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