Abdulbari Bener1, Abdulla O A A Al-Hamaq2, Elnour E Dafeeah3. 1. Department of Medical Statistics & Epidemiology, Hamad Medical Corporation, Doha, Qatar; Department of Public Health, Weill Cornell Medical College, Doha, Qatar; Department of Evidence for Population Health Unit, School of Epidemiology and Health Sciences, University of Manchester, Manchester, UK. Electronic address: abener@hmc.org.qa. 2. Qatar Diabetic Associations and Qatar Foundation, Doha, Qatar. 3. Department of Psychiatry, Psychology Unit, Rumailah Hospital, Hamad Medical Corporation, Doha, Qatar.
Abstract
BACKGROUND: Patients with schizophrenia are at greater risk for metabolic syndrome (MetS) and other cardiovascular risk factors. OBJECTIVE: The objective of the study was to examine the prevalence of metabolic syndrome (MetS) and its criteria among patients with schizophrenia (Sz) according to the revised criteria of NCEP ATP III and assess which component contributed to the increased risk of the MetS in schizophrenia patients. DESIGN: This was a matched case-control study. SETTING: Outpatient clinics of the Psychiatry department and Primary Health Care (PHC) Centers of the Supreme Council of Health, State of Qatar. SUBJECTS AND METHODS: The study was carried out among patients with schizophrenia (SZ) and healthy subjects above 20 years old. The study based on matched by age and gender of 233 cases and 466 controls. The survey was conducted from June 2010 to May 2011. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. Metabolic syndrome was defined using the National Cholesterol Education Program - Third Adult Treatment Panel (ATP III). RESULTS: The prevalence of metabolic syndrome among schizophrenic patients (36.5%) were significantly higher than healthy subjects (18.7%) (p<0.001). The prevalence of MetS in schizophrenic subjects was reported to be two times higher than in the general population. The MetS components were higher among schizophrenic patients than healthy subjects. Among the components of MetS, central obesity (63.9%) was the most common criteria among patients compared to healthy subjects (45.7%) (p<0.001). Schizophrenic patients (27%) were significantly obese than the healthy subjects (13.1%). Female schizophrenia patients were more likely to have three or more metabolic abnormalities compared to men. CONCLUSION: The study indicated that metabolic syndrome was highly prevalent in patients with schizophrenia. The female gender was significantly associated with a higher prevalence of metabolic syndrome. The identification and clinical management of this high risk group is of great importance.
BACKGROUND:Patients with schizophrenia are at greater risk for metabolic syndrome (MetS) and other cardiovascular risk factors. OBJECTIVE: The objective of the study was to examine the prevalence of metabolic syndrome (MetS) and its criteria among patients with schizophrenia (Sz) according to the revised criteria of NCEP ATP III and assess which component contributed to the increased risk of the MetS in schizophreniapatients. DESIGN: This was a matched case-control study. SETTING:Outpatient clinics of the Psychiatry department and Primary Health Care (PHC) Centers of the Supreme Council of Health, State of Qatar. SUBJECTS AND METHODS: The study was carried out among patients with schizophrenia (SZ) and healthy subjects above 20 years old. The study based on matched by age and gender of 233 cases and 466 controls. The survey was conducted from June 2010 to May 2011. Face to face interviews were conducted using a structured questionnaire followed by laboratory tests. Metabolic syndrome was defined using the National Cholesterol Education Program - Third Adult Treatment Panel (ATP III). RESULTS: The prevalence of metabolic syndrome among schizophrenicpatients (36.5%) were significantly higher than healthy subjects (18.7%) (p<0.001). The prevalence of MetS in schizophrenic subjects was reported to be two times higher than in the general population. The MetS components were higher among schizophrenicpatients than healthy subjects. Among the components of MetS, central obesity (63.9%) was the most common criteria among patients compared to healthy subjects (45.7%) (p<0.001). Schizophrenicpatients (27%) were significantly obese than the healthy subjects (13.1%). Female schizophreniapatients were more likely to have three or more metabolic abnormalities compared to men. CONCLUSION: The study indicated that metabolic syndrome was highly prevalent in patients with schizophrenia. The female gender was significantly associated with a higher prevalence of metabolic syndrome. The identification and clinical management of this high risk group is of great importance.
Authors: Bodyl A Brand; Yudith R A Haveman; Franciska de Beer; Janna N de Boer; Paola Dazzan; Iris E C Sommer Journal: Psychol Med Date: 2021-11-12 Impact factor: 10.592
Authors: Samer Hammoudeh; Hawra Al Lawati; Suhaila Ghuloum; Huma Iram; Arij Yehya; Imen Becetti; Nora Al-Fakhri; Hany Ghabrash; Mena Shehata; Nighat Ajmal; Iman Amro; Hira Safdar; Yassin Eltorki; Hassen Al-Amin Journal: Community Ment Health J Date: 2019-12-28