L Messerer1, S Bouzbid2, E Gourbdji3, R Mansouri4, F Bachi3. 1. Laboratoire de parasitologie-mycologie, faculté de médecine, Annaba, Algérie. Electronic address: leylamesserer@yahoo.fr. 2. Service d'épidémiologie et de médecine préventive, CHU d'Annaba, Annaba, Algérie. 3. Service de biologie parasitaire, institut Pasteur d'Algérie, Alger, Algérie. 4. Laboratoire de parasitologie-mycologie, faculté de médecine, Annaba, Algérie.
Abstract
BACKGROUND: The aim of the study was to estimate the seroprevalence and risk factors of toxoplasmosis in pregnant women in the department of Annaba, Algeria. METHODS: We performed a cross-sectional study with analytical purposes. The study was collaboration between the laboratory of Parasitology-Mycology, Faculty of Medicine of Annaba and Parasite Biology Department at the Pasteur Institute of Algeria. A total of 1028 pregnant women who underwent prenatal diagnosis/visit were included over a period of 4 years from January 2006 to December 2009. Immunoglobulin G and M were assayed, using the microparticle enzyme method. The avidity test was used to determine the date of contamination according to age of pregnancy. Search for the parasite was made by inoculation of the placenta and cord blood in white mice. The study compared mother-to-child serological profiles using Western Blot (WB) IgG and IgM. Direct (not well-cooked meat) and indirect (presence of cat, gardening) indicators were recorded to search for parasite exposure. RESULTS: Seroprevalence was 47.8 % (95 % CI: 44.8 to 51.0) and the rate of active toxoplasmosis was 1.1 % (95 % CI 0.6 to 1.8). According to their immune status, this was the first serology for 41 % (CI95 %: 38.0-44.0) of women; 12 % (CI95 %: 10.5-14.6) of primiparous women had only one serology test during their entire pregnancy. Major risk factors were consumption of poorly-cooked meat and exposure to cats. CONCLUSION: Toxoplasmosis during pregnancy is a serious issue and an effective prevention program is needed.
BACKGROUND: The aim of the study was to estimate the seroprevalence and risk factors of toxoplasmosis in pregnant women in the department of Annaba, Algeria. METHODS: We performed a cross-sectional study with analytical purposes. The study was collaboration between the laboratory of Parasitology-Mycology, Faculty of Medicine of Annaba and Parasite Biology Department at the Pasteur Institute of Algeria. A total of 1028 pregnant women who underwent prenatal diagnosis/visit were included over a period of 4 years from January 2006 to December 2009. Immunoglobulin G and M were assayed, using the microparticle enzyme method. The avidity test was used to determine the date of contamination according to age of pregnancy. Search for the parasite was made by inoculation of the placenta and cord blood in white mice. The study compared mother-to-child serological profiles using Western Blot (WB) IgG and IgM. Direct (not well-cooked meat) and indirect (presence of cat, gardening) indicators were recorded to search for parasite exposure. RESULTS: Seroprevalence was 47.8 % (95 % CI: 44.8 to 51.0) and the rate of active toxoplasmosis was 1.1 % (95 % CI 0.6 to 1.8). According to their immune status, this was the first serology for 41 % (CI95 %: 38.0-44.0) of women; 12 % (CI95 %: 10.5-14.6) of primiparous women had only one serology test during their entire pregnancy. Major risk factors were consumption of poorly-cooked meat and exposure to cats. CONCLUSION:Toxoplasmosis during pregnancy is a serious issue and an effective prevention program is needed.
Authors: Zafar Rasheed; Ali Shariq; Ghaida B AlQefari; Ghayda S Alwahbi; Amal I Aljuaythin; Fidaa S Alsuhibani; Daliyah F Alotaibi; Shahad S Aljohani; Ruqiah Alghasham; Thamir Alsaeed; Nada A Alharbi; Osamah Al Rugaie; Waleed Al Abdulmonem; Osama F Sharaf Journal: Womens Health (Lond) Date: 2021 Jan-Dec
Authors: Olaniran Olarinde; Oluyomi A Sowemimo; Ting-Wu Chuang; Chia-Mei Chou; Segun O Olasanmi; Kemisola Ikotun; Olaoluwa P Akinwale; Vincent P Gyang; Timothy Nwafor; Adeola Y Olukosi; Jer-Hwa Chang; Chia-Kwung Fan Journal: Pathog Glob Health Date: 2021-07-13 Impact factor: 3.735