BACKGROUND:Partial weight supported treadmill gait training (PWSTT) is widely used in rehabilitation of gait in patient with Parkinson’s Diseases (PD). However, its effect on blood pressure variability (BPV) and baroreflex sensitivity (BRS) in PD has not been studied. AIM: To evaluate the effect of conventional and treadmill gait training on BPV components and BRS. METHODS:Sixty patients with idiopathic PD were randomized into three groups. Twenty patients in control group were on only stable medication, 20 patients inconventional gait training (CGT) group (Stable medication with CGT) and 20 patients in PWSTT group (Stable medication with 20 % PWSTT). The CGT and PWSTT sessions were given for 30 min per day, 4 days per week, for 4 weeks (16 sessions). Groups were evaluated in their best ‘ON’ states. The beat-to-beat finger blood pressure (BP) was recorded for 10 min using a Finometer instrument (Finapres Medical Systems, The Netherlands). BPV and BRS results were derived from artifact-free 5-min segments using Nevrocard software. RESULTS:BRS showed a significant group with time interaction (F = 6.930; p = 0.003). Post-hoc analysis revealed that PWSTT group showed significant improvement in BRS (p < 0.001) after 4 weeks of training. No significant differences found in BPV parameters; systolic BP, diastolic BP, co-variance of systolic BP and low frequency component of systolic BP. CONCLUSIONS: Four weeks of PWSTT significantly improves BRS in patients with PD. It can be considered as a non-invasive method of influencing BRS for prevention of orthostatic BP fall in patients with PD.
RCT Entities:
BACKGROUND: Partial weight supported treadmill gait training (PWSTT) is widely used in rehabilitation of gait in patient with Parkinson’s Diseases (PD). However, its effect on blood pressure variability (BPV) and baroreflex sensitivity (BRS) in PD has not been studied. AIM: To evaluate the effect of conventional and treadmill gait training on BPV components and BRS. METHODS: Sixty patients with idiopathic PD were randomized into three groups. Twenty patients in control group were on only stable medication, 20 patients in conventional gait training (CGT) group (Stable medication with CGT) and 20 patients in PWSTT group (Stable medication with 20 % PWSTT). The CGT and PWSTT sessions were given for 30 min per day, 4 days per week, for 4 weeks (16 sessions). Groups were evaluated in their best ‘ON’ states. The beat-to-beat finger blood pressure (BP) was recorded for 10 min using a Finometer instrument (Finapres Medical Systems, The Netherlands). BPV and BRS results were derived from artifact-free 5-min segments using Nevrocard software. RESULTS: BRS showed a significant group with time interaction (F = 6.930; p = 0.003). Post-hoc analysis revealed that PWSTT group showed significant improvement in BRS (p < 0.001) after 4 weeks of training. No significant differences found in BPV parameters; systolic BP, diastolic BP, co-variance of systolic BP and low frequency component of systolic BP. CONCLUSIONS: Four weeks of PWSTT significantly improves BRS in patients with PD. It can be considered as a non-invasive method of influencing BRS for prevention of orthostatic BP fall in patients with PD.
Authors: Dominique Laude; Jean-Luc Elghozi; Arlette Girard; Elisabeth Bellard; Malika Bouhaddi; Paolo Castiglioni; Catherine Cerutti; Andrei Cividjian; Marco Di Rienzo; Jacques-Olivier Fortrat; Ben Janssen; John M Karemaker; Georges Lefthériotis; Gianfranco Parati; Pontus B Persson; Alberto Porta; Luc Quintin; Jacques Regnard; Heinz Rüdiger; Harald M Stauss Journal: Am J Physiol Regul Integr Comp Physiol Date: 2003-09-18 Impact factor: 3.619
Authors: Franca Barbic; Francesca Perego; Margherita Canesi; Michela Gianni; Sara Biagiotti; Giorgio Costantino; Giovanni Pezzoli; Alberto Porta; Alberto Malliani; Raffaello Furlan Journal: Hypertension Date: 2006-11-13 Impact factor: 10.190
Authors: Jacqueline A Osborne; Rachel Botkin; Cristina Colon-Semenza; Tamara R DeAngelis; Oscar G Gallardo; Heidi Kosakowski; Justin Martello; Sujata Pradhan; Miriam Rafferty; Janet L Readinger; Abigail L Whitt; Terry D Ellis Journal: Phys Ther Date: 2022-04-01
Authors: Jan Mehrholz; Joachim Kugler; Alexander Storch; Marcus Pohl; Kathleen Hirsch; Bernhard Elsner Journal: Cochrane Database Syst Rev Date: 2015-09-13