Literature DB >> 24656879

Let's go out of the breast: prevalence of extra-mammary findings and their characterization on breast MRI.

Marco Moschetta1, Michele Telegrafo2, Leonarda Rella3, Amato Antonio Stabile Ianora4, Giuseppe Angelelli5.   

Abstract

PURPOSE: The aim of this study is to assess the prevalence, the site and the nature of extra-mammary findings on breast magnetic resonance imaging (MRI) and to determine its accuracy in the characterization of the discovered lesions.
MATERIALS AND METHODS: A retrospective review of 308 female patients (mean age 50 ± 20) who underwent breast MRI with 1.5T device was performed. 125 out of 308 (40.5%) had a positive personal history of breast cancer (pre-operative n=80; follow-up n=45), while the remaining 183 without history of breast cancer (high familiar risk for breast cancer n=80; dense breast n=103). All incidental findings were characterized by means of additional imaging (US; Bone scintigraphy-MRI; CT-PET-CT).
RESULTS: 59 incidental findings were found in 53/308 (17%) examined patients. 9/59 incidental findings (15%) were confirmed to be malignant while the remaining 50/59 (84%) benign. The most common site was the liver (33/59; 55.8%), followed by the lung (6/59; 10.1%), bone (6/59; 10.1%), diaphragm (6/59; 10.1%) spleen (3/59; 5%), kidney (2/59; 3.4%), gall bladder (1/5; 1.5%), ascending aorta (1/59; 1.5%), thyroid (1/59; 1.5%). The incidence of malignant incidental findings resulted to be higher in the group of patients with personal breast cancer (36%) than in the other one (8%). By comparing MRI findings with the additional definitive imaging tools, breast MRI allowed a correct diagnosis in 58/59 cases with a diagnostic accuracy value of 98%.
CONCLUSION: Incidental extramammary findings on breast MRI are common. Benign lesions represent the most frequent findings, however malignant ones need to be searched especially in patients with personal history of breast cancer because they could influence the clinical patient management. Breast MRI can characterize incidental findings with high accuracy value.
Copyright © 2014 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Breast; Incidental findings; MRI

Mesh:

Year:  2014        PMID: 24656879     DOI: 10.1016/j.ejrad.2014.02.022

Source DB:  PubMed          Journal:  Eur J Radiol        ISSN: 0720-048X            Impact factor:   3.528


  5 in total

1.  Clinical Significance of Radiologically Detected Small Indeterminate Extra-Mammary Lesions in Breast Cancer Patients.

Authors:  Rachel Yanlin Chen; Rui Ying Goh; Hoi Ting Leung; Stephanie Cheng; Veronique Kiak Mien Tan; Clement Luck Khng Chia; Jerry Tiong Thye Goo; Marc Weijie Ong
Journal:  Eur J Breast Health       Date:  2022-07-01

2.  Incidental liver lesions on baseline breast MRI: Outcomes on subsequent abdominal imaging.

Authors:  Jill Gluskin; Sarah Eliades; Aradhna Raj; Varadan Sevilimedu; Richard Kinh Gian Do
Journal:  Clin Imaging       Date:  2022-02-16       Impact factor: 2.420

3.  Frequency and Clinical Significance of Extramammary Findings on Breast Magnetic Resonance Imaging.

Authors:  Sneha Phadke; Alexandra Thomas; Limin Yang; Catherine Moore; Chang Xia; Mary C Schroeder
Journal:  Clin Breast Cancer       Date:  2015-08-28       Impact factor: 3.225

4.  Extramammary findings on breast MRI: prevalence and imaging characteristics favoring malignancy detection: a retrospective analysis.

Authors:  Soung Moon Yang; Sung Hun Kim; Bong Joo Kang; Byung Joo Song
Journal:  World J Surg Oncol       Date:  2016-04-21       Impact factor: 2.754

5.  Prevalence of benign focal liver lesions: ultrasound investigation of 45,319 hospital patients.

Authors:  Tanja Eva-Maria Kaltenbach; Phillip Engler; Wolfgang Kratzer; Suemeyra Oeztuerk; Thomas Seufferlein; Mark Martin Haenle; Tilmann Graeter
Journal:  Abdom Radiol (NY)       Date:  2016-01
  5 in total

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