Adepitan A Owosho1, Elizabeth A Bilodeau2, John Vu3, Kurt F Summersgill4. 1. Resident, Oral and Maxillofacial Pathology, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA. Electronic address: owoshoaa@upmc.edu. 2. Assistant Professor, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA. 3. Assistant Professor, Department of Pathology, Division of Dermatopathology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA. 4. Associate Professor, Department of Diagnostic Sciences, University of Pittsburgh School of Dental Medicine, Pittsburgh, PA, USA.
Abstract
OBJECTIVE: The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses. STUDY DESIGN: Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 period. The histologic features were evaluated and categorized into 5 groups (I to V). Unstained deparaffinized sections of representative tissue from one case in each of groups I to IV were sent for spectrometric analysis, along with samples of 2 popular dermal fillers (Juvéderm and Radiesse). RESULTS: With the help of spectrometric analysis, we were able to correlate the histopathologic presentations with the specific type of dermal filler used.
OBJECTIVE: The aim of this study is to assess the different histopathologic presentations of dermal filler materials-induced foreign body reactions by spectrometric analyses. STUDY DESIGN: Sixteen cases of dermal filler foreign body reactions in the orofacial region were retrieved from the 2006-2013 period. The histologic features were evaluated and categorized into 5 groups (I to V). Unstained deparaffinized sections of representative tissue from one case in each of groups I to IV were sent for spectrometric analysis, along with samples of 2 popular dermal fillers (Juvéderm and Radiesse). RESULTS: With the help of spectrometric analysis, we were able to correlate the histopathologic presentations with the specific type of dermal filler used.