Hong Ma1, Howard J Cooke2, Qinghua Shi3. 1. State Key Laboratory of Genetic Engineering, Institute of Plant Biology, School of Life Sciences, Fudan University, Shanghai 200433, China. Electronic address: hongma@fudan.edu.cn. 2. CAS Institute of Physics, Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China; MRC Human Genetics Unit and Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh EH4 2XU, United Kingdom. Electronic address: howard.cooke@igmm.ed.ac.uk. 3. CAS Institute of Physics, Hefei National Laboratory for Physical Sciences at Microscale, School of Life Sciences, University of Science and Technology of China, Hefei 230027, China. Electronic address: qshi@ustc.edu.cn.