Literature DB >> 24655920

Ligand control of g protein-coupled receptor activity: new insights.

Rosalie K Crouch1, Masahiro Kono2.   

Abstract

In this issue of Chemistry & Biology, Srinivasan and colleagues describe their study of ligand-protein interactions in visual pigments. Comparing the more stable isomeric ligand 9-cis retinal to the physiologically occurring 11-cis retinal, they report differences in ligand specificity and opsin conformational stability not previously described for bleached rhodopsin.
Copyright © 2014 Elsevier Ltd. All rights reserved.

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Year:  2014        PMID: 24655920     DOI: 10.1016/j.chembiol.2014.03.001

Source DB:  PubMed          Journal:  Chem Biol        ISSN: 1074-5521


  2 in total

1.  Human Blue Cone Opsin Regeneration Involves Secondary Retinal Binding with Analog Specificity.

Authors:  Sundaramoorthy Srinivasan; Miguel A Fernández-Sampedro; Margarita Morillo; Eva Ramon; Mireia Jiménez-Rosés; Arnau Cordomí; Pere Garriga
Journal:  Biophys J       Date:  2018-03-27       Impact factor: 4.033

2.  Beyond spectral tuning: human cone visual pigments adopt different transient conformations for chromophore regeneration.

Authors:  Sundaramoorthy Srinivasan; Arnau Cordomí; Eva Ramon; Pere Garriga
Journal:  Cell Mol Life Sci       Date:  2015-09-19       Impact factor: 9.261

  2 in total

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