Literature DB >> 24655468

Aortic root enlargement in octogenarian patients results in less patient prosthesis mismatch.

Juan G Penaranda1, Kevin L Greason2, Sorin V Pislaru3, Hartzell V Schaff4, Richard C Daly4, Soon J Park4, Rakesh M Suri4, Harold M Burkhart4, Lyle D Joyce4, John M Stulak4, Joseph A Dearani4.   

Abstract

BACKGROUND: Aortic root enlargement has not been well studied as a modality to prevent patient prosthesis mismatch in octogenarian patients with a small aortic root.
METHODS: We reviewed the records of 117 octogenarian patients who received surgical aortic valve replacement (AVR) between 1993 and 2010. From this group, 87 patients received a 19-mm AVR (small aortic valve, SAV group) and 30 received an aortic root enlargement and a 21-mm AVR (aortic root enlargement, ARE group).
RESULTS: The median age of the patients was 84 years (range, 80 to 93) and there were 111 women (95%). Aortic cross-clamp time was 50 minutes (26 to 116) in the SAV group and 67 (26 to 136) in the ARE group (p=0.02). There were no differences in the operative morbidity or morality rates between the groups. Postoperative aortic valve area index was 0.77 cm2/m2 (0.25 to 1.47) in the SAV group and 1.06 (0.51 to 1.94) in the ARE group (p<0.001). Severe patient prosthesis mismatch occurred in 23 patients (32%) in the SAV group in comparison with 3 (12%) in the ARE group (p=0.04). There were no differences in the mid-term outcomes of New York Heart Association functional class (p=0.230) or survival between patients with or without mismatch (p=0.84).
CONCLUSIONS: Aortic root enlargement in octogenarian patients allows for insertion of larger aortic valve prostheses without any apparent increase in operative morbidity or mortality. The larger prostheses demonstrate better hemodynamic performance and less patient prosthesis mismatch, but no apparent functional or survival advantage.
Copyright © 2014 The Society of Thoracic Surgeons. Published by Elsevier Inc. All rights reserved.

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Year:  2014        PMID: 24655468     DOI: 10.1016/j.athoracsur.2013.11.050

Source DB:  PubMed          Journal:  Ann Thorac Surg        ISSN: 0003-4975            Impact factor:   4.330


  2 in total

Review 1.  Prosthesis-patient mismatch - what cardiac anesthesiologists need to know?

Authors:  Kathirvel Subramaniam; Soheyla Nazarnia
Journal:  Ann Card Anaesth       Date:  2017 Apr-Jun

2.  Prosthesis-Patient Mismatch after Surgical Aortic Valve Replacement: Neither Uncommon nor Harmless.

Authors:  Sérgio da Costa Rayol; Michel Pompeu Barros Oliveira Sá; Luiz Rafael Pereira Cavalcanti; Felipe Augusto Santos Saragiotto; Roberto Gouvea Silva Diniz; Frederico Browne Correia de Araujo E Sá; Alexandre Motta Menezes; Frederico Pires Vasconcelos Silva; Ricardo Carvalho Lima
Journal:  Braz J Cardiovasc Surg       Date:  2019-06-01
  2 in total

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