Hui-chun Xie1, Hong-Ping Han1, Zhi Chen2, Jian-Ping He3. 1. The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008 ; Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062. 2. The Key Laboratory of Education Ministry on Environments and Resources in Tibetan Plateau, Qinghai-Normal University, 38 West Wusi Road, Xining, 810008. 3. Shaanxi Normal University, 199 South Chang'an Road, Xi'an, 710062.
Abstract
BACKGROUND: The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemia mice. MATERIALS AND METHODS: Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined. RESULTS: Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner. CONCLUSION: We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.
BACKGROUND: The content of resveratrol is relatively high in Polygonum cuspidatum Sieb. et Zucc., and the resveratrol has the effect of blood vessel dilating, microcirculation improving, platelet aggregation inhibiting and anti-cancer. The objective of this paper was to study the effect of resveratrol on lipid metabolism in hyperlipidemiamice. MATERIALS AND METHODS: Through the establishment of an experimental mouse model of hyperlipidemia, the effect of resveratrol on change in total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-c), and low-density lipoprotein cholesterol (LDL-c) levels in mouse serum were determined. RESULTS:Resveratrol group can apparently reduce TC, TG, LDL-c and AI of hyperlipidemic mice in a dose effect manner. CONCLUSION: We concluded that resveratrol can effectively reduce blood lipid levels of hyperlipidemic mice.
Authors: M Grønbaek; U Becker; D Johansen; A Gottschau; P Schnohr; H O Hein; G Jensen; T I Sørensen Journal: Ann Intern Med Date: 2000-09-19 Impact factor: 25.391
Authors: M Jang; L Cai; G O Udeani; K V Slowing; C F Thomas; C W Beecher; H H Fong; N R Farnsworth; A D Kinghorn; R G Mehta; R C Moon; J M Pezzuto Journal: Science Date: 1997-01-10 Impact factor: 47.728