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Literature DB >> 2465190

A common antigenic determinant of vimentin and desmin defined by monoclonal antibody.

E Dráberová¹, P Dráber, F Havlícek, V Viklický.

Abstract

A monoclonal antibody, VI-01, to vimentin and desmin has been isolated from a fusion of mouse myeloma cells with immune spleen cells. The antibody appeared specific for vimentin of various species and smooth muscle desmin and did not recognize other intermediate filament proteins when cell lines and tissue sections were assayed in immunofluorescence and cell lysates in immunoblotting. The binding test with purified vimentin and desmin confirmed these results. The antibody can differentiate carcinomas from sarcomas in human diagnostic surgical pathology.

Entities: Disease Gene Species

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Year: 1986 PMID： 2465190

Source DB: PubMed Journal: Folia Biol (Praha) ISSN： 0015-5500 Impact factor: 0.906

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Cited

8 in total

1. Association of brain gamma-tubulins with alpha beta-tubulin dimers.

Authors: Vadym Sulimenko; Tetyana Sulimenko; Slobodan Poznanovic; Volodymyr Nechiporuk-Zloy; Konrad J Böhm; Libor Macurek; Eberhard Unger; Pavel Dráber
Journal: Biochem J Date: 2002-08-01 Impact factor: 3.857

2. Expression of phosphorylated high molecular weight neurofilament protein (NF-H) and vimentin in human developing dorsal root ganglia and spinal cord.

Authors: Z Lukás; P Dráber; J Bucek; E Dráberová; V Viklický; S Dolezel
Journal: Histochemistry Date: 1993-12

3. Post-translational modifications and multiple tubulin isoforms in Nicotiana tabacum L. cells.

Authors: A Smertenko; Y Blume; V Viklický; Z Opatrný; P Dráber
Journal: Planta Date: 1997 Impact factor: 4.116

4. Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells.

Authors: Yaroslav Blume; Alla Yemets; Yarina Sheremet; Alexey Nyporko; Vadym Sulimenko; Tetyana Sulimenko; Pavel Dráber
Journal: BMC Plant Biol Date: 2010-02-18 Impact factor: 4.215

A common antigenic determinant of vimentin and desmin defined by monoclonal antibody.

1. Association of brain gamma-tubulins with alpha beta-tubulin dimers.

2. Expression of phosphorylated high molecular weight neurofilament protein (NF-H) and vimentin in human developing dorsal root ganglia and spinal cord.

3. Post-translational modifications and multiple tubulin isoforms in Nicotiana tabacum L. cells.

4. Exposure of beta-tubulin regions defined by antibodies on an Arabidopsis thaliana microtubule protofilament model and in the cells.

5. Immunocytochemistry and heterogeneity of rat brain vimentin.

6. Pontin is localized in nucleolar fibrillar centers.

7. Expression of vimentin and glial fibrillary acidic protein in human developing spinal cord.

8. Glycol porphyrin derivatives and temoporfin elicit resistance to photodynamic therapy by different mechanisms.