Literature DB >> 24651822

Insights into low molecular mass organic gelators: a focus on drug delivery and tissue engineering applications.

Kathryn J Skilling1, Francesca Citossi, Tracey D Bradshaw, Marianne Ashford, Barrie Kellam, Maria Marlow.   

Abstract

In recent years low molecular mass organic gelators (LMOGs) have gained increasing interest as an alternative biomaterial to polymer derived gels, with potential applications in drug delivery and tissue engineering. LMOGs are small organic molecules which self-assemble in water or organic solvents forming a 3D network that entraps the liquid phase resulting in gel formation. In this review, we report the classification of LMOGs into hydrogelators and gelators of organic solvents and we discuss the techniques commonly used to characterise the gels of these gelators with particular reference to specific applications of LMOGs in drug delivery and tissue engineering.

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Year:  2014        PMID: 24651822     DOI: 10.1039/c3sm52244j

Source DB:  PubMed          Journal:  Soft Matter        ISSN: 1744-683X            Impact factor:   3.679


  35 in total

Review 1.  Supramolecular Hydrogelators and Hydrogels: From Soft Matter to Molecular Biomaterials.

Authors:  Xuewen Du; Jie Zhou; Junfeng Shi; Bing Xu
Journal:  Chem Rev       Date:  2015-12-08       Impact factor: 60.622

Review 2.  Recently Developed Carbohydrate Based Gelators and Their Applications.

Authors:  Joedian Morris; Jonathan Bietsch; Kristen Bashaw; Guijun Wang
Journal:  Gels       Date:  2021-02-26

Review 3.  Personal Perspective on Understanding Low Molecular Weight Gels.

Authors:  Dave J Adams
Journal:  J Am Chem Soc       Date:  2022-06-17       Impact factor: 16.383

Review 4.  Ultrashort Peptide Self-Assembly: Front-Runners to Transport Drug and Gene Cargos.

Authors:  Seema Gupta; Indu Singh; Ashwani K Sharma; Pradeep Kumar
Journal:  Front Bioeng Biotechnol       Date:  2020-05-29

Review 5.  New Developments in Medical Applications of Hybrid Hydrogels Containing Natural Polymers.

Authors:  Cornelia Vasile; Daniela Pamfil; Elena Stoleru; Mihaela Baican
Journal:  Molecules       Date:  2020-03-27       Impact factor: 4.411

6.  Shaping and Patterning Supramolecular Materials─Stem Cell-Compatible Dual-Network Hybrid Gels Loaded with Silver Nanoparticles.

Authors:  Carmen C Piras; Clare S Mahon; Paul G Genever; David K Smith
Journal:  ACS Biomater Sci Eng       Date:  2022-04-01

7.  Synthesis and characterization of pH responsive D-glucosamine based molecular gelators.

Authors:  Navneet Goyal; Hari P R Mangunuru; Bargav Parikh; Sonu Shrestha; Guijun Wang
Journal:  Beilstein J Org Chem       Date:  2014-12-23       Impact factor: 2.883

8.  Multi-component hybrid hydrogels - understanding the extent of orthogonal assembly and its impact on controlled release.

Authors:  Vânia M P Vieira; Laura L Hay; David K Smith
Journal:  Chem Sci       Date:  2017-08-24       Impact factor: 9.825

9.  Novel walnut peptide-selenium hybrids with enhanced anticancer synergism: facile synthesis and mechanistic investigation of anticancer activity.

Authors:  Wenzhen Liao; Rong Zhang; Chenbo Dong; Zhiqiang Yu; Jiaoyan Ren
Journal:  Int J Nanomedicine       Date:  2016-04-11

10.  Urethane tetrathiafulvalene derivatives: synthesis, self-assembly and electrochemical properities.

Authors:  Xiang Sun; Guoqiao Lai; Zhifang Li; Yuwen Ma; Xiao Yuan; Yongjia Shen; Chengyun Wang
Journal:  Beilstein J Org Chem       Date:  2015-11-27       Impact factor: 2.883

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