M M Greene1, K Patra2, S Khan2, J S Karst1, M N Nelson1, J M Silvestri2. 1. 1] Department of Behavioral Sciences, Rush University Medical Center, Chicago, IL, USA [2] Department of Pediatrics, Rush University Medical Center, Chicago, IL, USA. 2. Department of Pediatrics, Rush University Medical Center, Chicago, IL, USA.
Abstract
OBJECTIVE: To examine the association between cardiorespiratory events (CRE) and neurodevelopmental (ND) outcome at 8 and 20 months corrected age (CA) in a contemporary extremely low birth weight (ELBW )cohort. STUDY DESIGN: Retrospective chart review of 98 ELBW infants born in 2009 to 2010 who completed ND assessments at 8 and 20 months CA. Neonatal, sociodemographic, CRE and ND data were collected. ND outcome measures included neurologic examination and results from the Bayley Scales of Infant and Toddler Development-III. Multiple regression analyses adjusted for the impact of neonatal risk factors on ND outcome. RESULT: After adjusting for neonatal and social variables, greater frequency of CRE was related to worse language scores at 8 months, while CRE of greater severity were related to worse language at 20 months CA. CONCLUSION: CRE in ELBW infants have impact on language development in the first two years of life.
OBJECTIVE: To examine the association between cardiorespiratory events (CRE) and neurodevelopmental (ND) outcome at 8 and 20 months corrected age (CA) in a contemporary extremely low birth weight (ELBW )cohort. STUDY DESIGN: Retrospective chart review of 98 ELBW infants born in 2009 to 2010 who completed ND assessments at 8 and 20 months CA. Neonatal, sociodemographic, CRE and ND data were collected. ND outcome measures included neurologic examination and results from the Bayley Scales of Infant and Toddler Development-III. Multiple regression analyses adjusted for the impact of neonatal risk factors on ND outcome. RESULT: After adjusting for neonatal and social variables, greater frequency of CRE was related to worse language scores at 8 months, while CRE of greater severity were related to worse language at 20 months CA. CONCLUSION: CRE in ELBW infants have impact on language development in the first two years of life.
Authors: Betty R Vohr; Brenda B Poindexter; Anna M Dusick; Leslie T McKinley; Linda L Wright; John C Langer; W Kenneth Poole Journal: Pediatrics Date: 2006-07 Impact factor: 7.124
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