Literature DB >> 24651008

Therapeutic opportunities for medulloblastoma come of age.

James M Olson1.   

Abstract

In this issue of Cancer Cell, Kool and colleagues reveal clear genetically defined subclasses of the sonic hedgehog (SHH) subclass of medulloblastoma. This molecular dissection of the SHH subclass is not simply a cutting-edge advance; the data have profound impact on clinical trial design and decision-making.
Copyright © 2014 Elsevier Inc. All rights reserved.

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Year:  2014        PMID： 24651008      PMCID： PMC4035234          DOI： 10.1016/j.ccr.2014.03.003

Source DB:  PubMed          Journal:  Cancer Cell        ISSN： 1535-6108            Impact factor:   31.743


  9 in total

1.  Outcome of children with metastatic medulloblastoma treated with carboplatin during craniospinal radiotherapy: a Children's Oncology Group Phase I/II study.

Authors:  Regina I Jakacki; Peter C Burger; Tianni Zhou; Emiko J Holmes; Mehmet Kocak; Arzu Onar; Joel Goldwein; Minesh Mehta; Roger J Packer; Nancy Tarbell; Charles Fitz; Gilbert Vezina; Joanne Hilden; Ian F Pollack
Journal:  J Clin Oncol       Date:  2012-06-04       Impact factor: 44.544

2.  Phase III study of craniospinal radiation therapy followed by adjuvant chemotherapy for newly diagnosed average-risk medulloblastoma.

Authors:  Roger J Packer; Amar Gajjar; Gilbert Vezina; Lucy Rorke-Adams; Peter C Burger; Patricia L Robertson; Lisa Bayer; Deborah LaFond; Bernadine R Donahue; MaryAnne H Marymont; Karin Muraszko; James Langston; Richard Sposto
Journal:  J Clin Oncol       Date:  2006-09-01       Impact factor: 44.544

3.  Multiagent chemotherapy and deferred radiotherapy in infants with malignant brain tumors: a report from the Children's Cancer Group.

Authors:  J Russell Geyer; Richard Sposto; Mark Jennings; James M Boyett; Richard A Axtell; David Breiger; Emmett Broxson; Bernadine Donahue; Jonathan L Finlay; Joel W Goldwein; Linda A Heier; Dennis Johnson; Claire Mazewski; Douglas C Miller; Roger Packer; Diane Puccetti; Jerilynn Radcliffe; May Lin Tao; Tania Shiminski-Maher
Journal:  J Clin Oncol       Date:  2005-10-20       Impact factor: 44.544

Review 4.  Children's Oncology Group's 2013 blueprint for research: central nervous system tumors.

Authors:  Amar Gajjar; Roger J Packer; N K Foreman; Kenneth Cohen; Daphne Haas-Kogan; Thomas E Merchant
Journal:  Pediatr Blood Cancer       Date:  2012-12-19       Impact factor: 3.167

5.  Medulloblastoma growth inhibition by hedgehog pathway blockade.

Authors:  David M Berman; Sunil S Karhadkar; Andrew R Hallahan; Joel I Pritchard; Charles G Eberhart; D Neil Watkins; James K Chen; Michael K Cooper; Jussi Taipale; James M Olson; Philip A Beachy
Journal:  Science       Date:  2002-08-30       Impact factor: 47.728

6.  Genome sequencing of SHH medulloblastoma predicts genotype-related response to smoothened inhibition.

Authors:  Marcel Kool; David T W Jones; Natalie Jäger; Paul A Northcott; Trevor J Pugh; Volker Hovestadt; Rosario M Piro; L Adriana Esparza; Shirley L Markant; Marc Remke; Till Milde; Franck Bourdeaut; Marina Ryzhova; Dominik Sturm; Elke Pfaff; Sebastian Stark; Sonja Hutter; Huriye Seker-Cin; Pascal Johann; Sebastian Bender; Christin Schmidt; Tobias Rausch; David Shih; Jüri Reimand; Laura Sieber; Andrea Wittmann; Linda Linke; Hendrik Witt; Ursula D Weber; Marc Zapatka; Rainer König; Rameen Beroukhim; Guillaume Bergthold; Peter van Sluis; Richard Volckmann; Jan Koster; Rogier Versteeg; Sabine Schmidt; Stephan Wolf; Chris Lawerenz; Cynthia C Bartholomae; Christof von Kalle; Andreas Unterberg; Christel Herold-Mende; Silvia Hofer; Andreas E Kulozik; Andreas von Deimling; Wolfram Scheurlen; Jörg Felsberg; Guido Reifenberger; Martin Hasselblatt; John R Crawford; Gerald A Grant; Nada Jabado; Arie Perry; Cynthia Cowdrey; Sydney Croul; Gelareh Zadeh; Jan O Korbel; Francois Doz; Olivier Delattre; Gary D Bader; Martin G McCabe; V Peter Collins; Mark W Kieran; Yoon-Jae Cho; Scott L Pomeroy; Olaf Witt; Benedikt Brors; Michael D Taylor; Ulrich Schüller; Andrey Korshunov; Roland Eils; Robert J Wechsler-Reya; Peter Lichter; Stefan M Pfister
Journal:  Cancer Cell       Date:  2014-03-17       Impact factor: 31.743

7.  A cancer family syndrome in twenty-four kindreds.

Authors:  F P Li; J F Fraumeni; J J Mulvihill; W A Blattner; M G Dreyfus; M A Tucker; R W Miller
Journal:  Cancer Res       Date:  1988-09-15       Impact factor: 12.701

8.  Subgroup-specific prognostic implications of TP53 mutation in medulloblastoma.

Authors:  Nataliya Zhukova; Vijay Ramaswamy; Marc Remke; Elke Pfaff; David J H Shih; Dianna C Martin; Pedro Castelo-Branco; Berivan Baskin; Peter N Ray; Eric Bouffet; André O von Bueren; David T W Jones; Paul A Northcott; Marcel Kool; Dominik Sturm; Trevor J Pugh; Scott L Pomeroy; Yoon-Jae Cho; Torsten Pietsch; Marco Gessi; Stefan Rutkowski; Laszlo Bognar; Almos Klekner; Byung-Kyu Cho; Seung-Ki Kim; Kyu-Chang Wang; Charles G Eberhart; Michelle Fevre-Montange; Maryam Fouladi; Pim J French; Max Kros; Wieslawa A Grajkowska; Nalin Gupta; William A Weiss; Peter Hauser; Nada Jabado; Anne Jouvet; Shin Jung; Toshihiro Kumabe; Boleslaw Lach; Jeffrey R Leonard; Joshua B Rubin; Linda M Liau; Luca Massimi; Ian F Pollack; Young Shin Ra; Erwin G Van Meir; Karel Zitterbart; Ulrich Schüller; Rebecca M Hill; Janet C Lindsey; Ed C Schwalbe; Simon Bailey; David W Ellison; Cynthia Hawkins; David Malkin; Steven C Clifford; Andrey Korshunov; Stefan Pfister; Michael D Taylor; Uri Tabori
Journal:  J Clin Oncol       Date:  2013-07-08       Impact factor: 44.544

9.  Medulloblastoma Down Under 2013: a report from the third annual meeting of the International Medulloblastoma Working Group.

Authors:  Nicholas G Gottardo; Jordan R Hansford; Jacqueline P McGlade; Frank Alvaro; David M Ashley; Simon Bailey; David L Baker; Franck Bourdeaut; Yoon-Jae Cho; Moira Clay; Steven C Clifford; Richard J Cohn; Catherine H Cole; Peter B Dallas; Peter Downie; François Doz; David W Ellison; Raelene Endersby; Paul G Fisher; Timothy Hassall; John A Heath; Hilary L Hii; David T W Jones; Reimar Junckerstorff; Stewart Kellie; Marcel Kool; Rishi S Kotecha; Peter Lichter; Stephen J Laughton; Sharon Lee; Geoff McCowage; Paul A Northcott; James M Olson; Roger J Packer; Stefan M Pfister; Torsten Pietsch; Barry Pizer; Scott L Pomeroy; Marc Remke; Giles W Robinson; Stefan Rutkowski; Tobias Schoep; Anang A Shelat; Clinton F Stewart; Michael Sullivan; Michael D Taylor; Brandon Wainwright; Thomas Walwyn; William A Weiss; Dan Williamson; Amar Gajjar
Journal:  Acta Neuropathol       Date:  2013-11-22       Impact factor: 17.088
  9 in total
  1 in total

1.  Inhibition of WNT signaling attenuates self-renewal of SHH-subgroup medulloblastoma.

Authors:  J Rodriguez-Blanco; L Pednekar; C Penas; B Li; V Martin; J Long; E Lee; W A Weiss; C Rodriguez; N Mehrdad; D M Nguyen; N G Ayad; P Rai; A J Capobianco; D J Robbins
Journal:  Oncogene       Date:  2017-07-17       Impact factor: 9.867
  1 in total

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