| Literature DB >> 24651005 |
Vedran Radojcic1, Ivan Maillard2.
Abstract
In this issue of Cancer Cell, Cao and colleagues identify an FGF4/Jagged1-driven crosstalk between tumor cells and their vascular niche that activates Notch signaling, sustaining the aggressiveness of certain mouse and human B cell lymphomas. These findings identify new therapeutic opportunities to target pathogenic angiocrine functions in cancer.Entities:
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Year: 2014 PMID: 24651005 PMCID: PMC4040245 DOI: 10.1016/j.ccr.2014.03.001
Source DB: PubMed Journal: Cancer Cell ISSN: 1535-6108 Impact factor: 31.743