| Literature DB >> 24650975 |
Anupama Goel1, Wen Fan2, Amit A Patel3, Madhuri Devabhaktuni3, Michael L Grossbard2.
Abstract
Nodular lymphocyte predominant Hodgkin lymphoma (NLPHL) is an uncommon variant of classical Hodgkin lymphoma. It is characterized histologically by presence of lymphohistiocytic cells which have B-cell phenotype, are positive for CD19, CD20, CD45, CD79a, BOB.1, Oct.2, and negative for CD15 and CD30. Patients often present with early stage of disease and do not have classical B symptoms. The clinical behavior appears to mimic that of an indolent non-Hodgkin lymphoma more than that of classical Hodgkin disease. The purpose of the present report is to define the biology of NLPHL, review its clinical presentation, and summarize the available clinical data regarding treatment.Entities:
Keywords: Hodgkin lymphoma; LP cell; NLPHL; Popcorn cell; Reed Sternberg cells
Mesh：
Year: 2014 PMID： 24650975 DOI： 10.1016/j.clml.2014.01.006
Source DB: PubMed Journal: Clin Lymphoma Myeloma Leuk ISSN： 2152-2669