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Literature DB >> 24649296

Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract.

Michael Hejna¹, Peter Birner², Matthias Preusser¹, Christiane M R Thallinger³, Nina Worel⁴, Reza Asari⁵, Werner Dolak⁶, Rainer Schmid⁷, Sebastian F Schoppmann⁵, Markus Raderer³.

Abstract

The assessment of the human epidermal growth factor receptor-2 (HER-2) status has become a routine diagnostic procedure for patients with advanced-stage gastroesophageal adenocarcinoma. The aim of this study was to evaluate the possible correlation between the HER-2 status and the ABO blood group. HER-2 status determination and routine ABO typing was performed according to current standards. We evaluated the correlation between the HER-2 status and the ABO and Rhesus (Rh) system in 100 consecutive patients with adenocarcinoma of the upper gastrointestinal tract. There were no significant differences between HER-2 status and ABO and Rh system. Furthermore, no correlation was observed between the HER-2 status and the ABO and Rh type in patients with adenocarcinoma of the upper gastrointestinal tract.

Entities: Disease Gene Species

Keywords: adenocarcinoma; blood group; gastroesophageal cancer; human epidermal growth factor receptor-2 status

Year: 2013 PMID： 24649296 PMCID： PMC3915671 DOI： 10.3892/mco.2013.181

Source DB: PubMed Journal: Mol Clin Oncol ISSN： 2049-9450

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Lack of correlation between blood group and HER-2 status in adenocarcinomas of the upper gastrointestinal tract.

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