| Literature DB >> 24649209 |
Murat Elli1, Sema Yilmaz1, Ramazan Aydin2, Sadriye Murat3, Meltem Ceyhan Bilgici2, Ayhan Dagdemir1.
Abstract
Relapsed or refractory B-cell non-Hodgkin's lymphoma (B-NHL) patients have a poor prognosis. New treatment modalities have been used to improve survival rates in children with relapsed or refractory B-NHL. CD20 is expressed in >98% of childhood B-NHL and a chimeric anti-CD20 monoclonal antibody, rituximab, is increasingly being used at relapse. The aim of the present study was to determine the efficacy of rituximab on relapsed B-NHL. Three B-NHL cases were treated successfully with a combination of intensive chemotherapy protocol plus rituximab.Entities:
Keywords: children; non-Hodgkin’s lymphoma; relapse; rituximab
Year: 2013 PMID: 24649209 PMCID: PMC3915537 DOI: 10.3892/mco.2013.88
Source DB: PubMed Journal: Mol Clin Oncol ISSN: 2049-9450