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Literature DB >> 24647552

Molecular typing of canine distemper virus strains reveals the presence of a new genetic variant in South America.

Nicolás Sarute¹, Ruben Pérez, Jaime Aldaz, Amauri A Alfieri, Alice F Alfieri, Daniela Name, Jessika Llanes, Martín Hernández, Lourdes Francia, Yanina Panzera.

Abstract

Canine distemper virus (CDV, Paramyxoviridae, Morbillivirus) is the causative agent of a severe infectious disease affecting terrestrial and marine carnivores worldwide. Phylogenetic relationships and the genetic variability of the hemagglutinin (H) protein and the fusion protein signal-peptide (Fsp) allow for the classification of field strains into genetic lineages. Currently, there are nine CDV lineages worldwide, two of them co-circulating in South America. Using the Fsp-coding region, we analyzed the genetic variability of strains from Uruguay, Brazil, and Ecuador, and compared them with those described previously in South America and other geographical areas. The results revealed that the Brazilian and Uruguayan strains belong to the already described South America lineage (EU1/SA1), whereas the Ecuadorian strains cluster in a new clade, here named South America 3, which may represent the third CDV lineage described in South America.

Entities: Disease Species

Mesh：

Substances：
Hemagglutinins, Viral

Year: 2014 PMID： 24647552 DOI： 10.1007/s11262-014-1054-z

Source DB: PubMed Journal: Virus Genes ISSN： 0920-8569 Impact factor: 2.332

17 in total

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Journal: J Zoo Wildl Med Date: 2000-12 Impact factor: 0.776

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Journal: J Clin Microbiol Date: 1999-11 Impact factor: 5.948

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Journal: J Virol Date: 2002-05 Impact factor: 5.103

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Journal: Vet Microbiol Date: 1993-10 Impact factor: 3.293

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Authors: Timothy Y Woma; Moritz van Vuuren; Ana-Mari Bosman; Melvyn Quan; Marinda Oosthuizen
Journal: Vet Microbiol Date: 2009-11-18 Impact factor: 3.293

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Journal: Vet Microbiol Date: 2007-06-06 Impact factor: 3.293

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Authors: Nicolás Sarute; Marina Gallo Calderón; Ruben Pérez; José La Torre; Martín Hernández; Lourdes Francia; Yanina Panzera
Journal: PLoS One Date: 2013-05-13 Impact factor: 3.240

7 in total

1. Phylodynamic analysis of the canine distemper virus hemagglutinin gene.

Authors: Guan-Ming Ke; Chin-Hsiang Ho; Meng-Jung Chiang; Bintou Sanno-Duanda; Cheng-Shu Chung; Maw-Yeong Lin; Yong-Ying Shi; Ming-Hui Yang; Yu-Chang Tyan; Pao-Chi Liao; Pei-Yu Chu
Journal: BMC Vet Res Date: 2015-07-25 Impact factor: 2.741

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Authors: Nicolás Sarute; María V Delgado; Lucía Carrau; Alejandro Benech; Lourdes Francia; Ruben Pérez; Yanina Panzera
Journal: Genome Announc Date: 2014-10-23

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Journal: Infect Genet Evol Date: 2020-06-21 Impact factor: 3.342

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Authors: Rebecca P Wilkes; Yun-Long Tsai; Pei-Yu Lee; Fu-Chun Lee; Hsiao-Fen Grace Chang; Hwa-Tang Thomas Wang
Journal: BMC Vet Res Date: 2014-09-09 Impact factor: 2.741