Literature DB >> 24647507

Many diabetic total joint arthroplasty candidates are unable to achieve a preoperative hemoglobin A1c goal of 7% or less.

Nicholas J Giori1, Laura S Ellerbe2, Thomas Bowe2, Shalini Gupta2, Alex H S Harris2.   

Abstract

BACKGROUND: Patients with poorly controlled diabetes have an elevated risk of complications and death following total joint arthroplasty. Some centers set a threshold hemoglobin A1c (HbA1c) value above which surgery is delayed pending better glycemic control. The purpose of this study was to examine how many diabetic patients scheduled for primary total joint arthroplasty underwent a delay because of an HbA1c value of >7.0%, how many subsequently achieved this goal, and how much time was necessary to achieve this goal.
METHODS: The study involved a retrospective chart review at one Veterans Affairs medical center. Patients with an HbA1c of >7.0% were referred to their primary care provider for better diabetic control. Unless reduction of the HbA1c to ≤7.0% was deemed medically inadvisable, surgery proceeded only after the patient returned with an HbA1c of ≤7.0%.
RESULTS: A total of 404 diabetic patients were scheduled for total joint arthroplasty. In fifty-nine cases, the surgery was delayed because of an HbA1c of >7.0%. Thirty-five of these patients were able to reduce the HbA1c level to ≤7.0% after a median of 141 days (range, seven to 1043 days), and twenty-four failed to achieve this goal. If an HbA1c goal of ≤8.0% had been used, the surgery would have been delayed in thirty cases, and twenty-one of these patients would have subsequently achieved the goal.
CONCLUSIONS: When establishing a goal designed to reduce perioperative risks, there should be an expectation that the goal is achievable. Overall, an HbA1c of ≤7.0% was achieved by 380 of the 404 diabetic patients (94%; 95% confidence interval [CI], 91% to 96%), but it was achieved by only thirty-five (59%; 95% CI, 46% to 72%) of the fifty-nine patients presenting with an HbA1c of >7.0%. An HbA1c of 8.0% was achieved by 395 (98%; 95% CI, 96% to 99%) of the diabetic patients and by twenty-one (70%; 95% CI, 50% to 85%) of the thirty patients presenting with an HbA1c of >8.0%. Achieving an HbA1c value of ≤7.0% may not be possible for certain diabetic patients, and such a requirement may risk access to total joint arthroplasty treatment.

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Year:  2014        PMID: 24647507     DOI: 10.2106/JBJS.L.01631

Source DB:  PubMed          Journal:  J Bone Joint Surg Am        ISSN: 0021-9355            Impact factor:   5.284


  12 in total

1.  Do patients with insulin-dependent and noninsulin-dependent diabetes have different risks for complications after arthroplasty?

Authors:  Francis Lovecchio; Matthew Beal; Mary Kwasny; David Manning
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2.  Does Preoperative Glycemic Control Restore Immune Defense Against Implant-related Infection in Mice With Diabetes?

Authors:  Junqing Lin; Tengli Huang; Haifeng Wei; Bingbo Bao; Tao Gao; Xianyou Zheng; Hongyi Zhu
Journal:  Clin Orthop Relat Res       Date:  2021-11-19       Impact factor: 4.176

Review 3.  Preoperative Patient Optimization in Total Joint Arthroplasty-The Paradigm Shift from Preoperative Clearance: A Narrative Review.

Authors:  Aoife MacMahon; Sandesh S Rao; Yash P Chaudhry; Syed A Hasan; Jeremy A Epstein; Vishal Hegde; Daniel J Valaik; Julius K Oni; Robert S Sterling; Harpal S Khanuja
Journal:  HSS J       Date:  2021-07-30

4.  Letter to the Editor on "Implementation of Preoperative Screening Criteria Lowers Infection and Complication Rates Following Elective Total Hip Arthroplasty and Total Knee Arthroplasty in a Veteran Population".

Authors:  Nicholas J Giori; Alex H S Harris
Journal:  J Arthroplasty       Date:  2018-02-22       Impact factor: 4.757

Review 5.  Patient-related medical risk factors for periprosthetic joint infection of the hip and knee.

Authors:  Aleeson Eka; Antonia F Chen
Journal:  Ann Transl Med       Date:  2015-09

6.  Eligibility Criteria for Lower Extremity Joint Replacement May Worsen Racial and Socioeconomic Disparities.

Authors:  Abigail Y Wang; Michelle S Wong; Casey Jo Humbyrd
Journal:  Clin Orthop Relat Res       Date:  2018-12       Impact factor: 4.176

7.  Blood Glucose Levels in Diabetic Patients Following Corticosteroid Injections into the Subacromial Space of the Shoulder.

Authors:  Alexander W Aleem; Usman Ali M Syed; Thema Nicholson; Charles L Getz; Surena Namdari; Pedro K Beredjiklian; Joseph A Abboud
Journal:  Arch Bone Jt Surg       Date:  2017-09

Review 8.  Management of Hyperglycemia and Diabetes in Orthopedic Surgery.

Authors:  Funke Akiboye; Gerry Rayman
Journal:  Curr Diab Rep       Date:  2017-02       Impact factor: 4.810

9.  Achieving a Preoperative Target HbA1c of < 69 mmol/mol in Elective Vascular and Orthopedic Surgery: A Retrospective Single Center Observational Study.

Authors:  Celina Uppal; Andrew Blanshard; Rupa Ahluwalia; Ketan Dhatariya
Journal:  Diabetes Ther       Date:  2019-08-29       Impact factor: 2.945

10.  Clinical Characteristics of Patients with Type 2 Diabetes Mellitus Receiving a Primary Total Knee or Hip Arthroplasty.

Authors:  Annalisa Na; Laurie Jansky; Zbigniew Gugala
Journal:  J Diabetes Res       Date:  2019-11-19       Impact factor: 4.011

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