Literature DB >> 24646620

Self-inflating bags versus T-piece resuscitator to deliver sustained inflations in a preterm lamb model.

M Thio, J A Dawson, T J Moss, R Galinsky, A Rafferty, S B Hooper, P G Davis.   

Abstract

OBJECTIVE: In neonatal resuscitation, the use of a sustained inflation (SI) may facilitate lung aeration. Previous studies comparing different resuscitation devices have shown that one model of self-inflating bag (SIB) could not deliver an SI. We aimed to compare the delivery of an SI using four SIBs with that of a T-piece. STUDY
DESIGN: In intubated preterm lambs, we compared four models of SIB fitted with a positive end expiratory pressure (PEEP) valve to a T-piece using a gas flow of 8 L/min. Four operators aimed to deliver three SIs of 20 cm H₂O for 30 s. The study was repeated with the PEEP valve removed and again with no flow. We measured duration of SI, average inflation pressure (IP) and analysed the shape of the pressure curves.
RESULTS: 204 combinations were analysed. Mean (SD) duration of SI was Ambu 6(2)s, Laerdal 14(8)s, Parker Healthcare 5(1)s, Mayo Healthcare 33(2)s and T-piece 33(1)s. Mean (SD) average IP was Ambu 17(3)cm H₂O, Laerdal 17(3)cm H₂O, Parker Healthcare 12(5)cm H₂O, Mayo Healthcare 21(2)cm H₂O and T-piece 20(0)cm H₂O. Duration of SI and average IP was significantly different between SIBs (all p<0.001). The findings were substantially unchanged when PEEP valve and flow were removed (all p>0.05). Only the Mayo system delivered SIs with duration and average IP not significantly different from the T-piece (p>0.05).
CONCLUSIONS: The performance of the four SIBs tested varied considerably. Some are able to deliver an SI even in the absence of gas flow. This may be useful in a resource-limited setting with no gas supply.

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Mesh:

Year:  2014        PMID: 24646620     DOI: 10.1136/archdischild-2013-305239

Source DB:  PubMed          Journal:  Arch Dis Child Fetal Neonatal Ed        ISSN: 1359-2998            Impact factor:   5.747


  3 in total

1.  Manual Ventilation and Sustained Lung Inflation in an Experimental Model: Influence of Equipment Type and Operator's Training.

Authors:  Cristiane do Prado; Ruth Guinsburg; Maria Fernanda Branco de Almeida; Renata Suman Mascaretti; Luciana Assis Vale; Luciana Branco Haddad; Celso Moura Rebello
Journal:  PLoS One       Date:  2016-02-09       Impact factor: 3.240

Review 2.  Ventilation, oxidative stress and risk of brain injury in preterm newborn.

Authors:  Laura Cannavò; Immacolata Rulli; Raffaele Falsaperla; Giovanni Corsello; Eloisa Gitto
Journal:  Ital J Pediatr       Date:  2020-07-23       Impact factor: 2.638

Review 3.  Unraveling the Links Between the Initiation of Ventilation and Brain Injury in Preterm Infants.

Authors:  Samantha K Barton; Mary Tolcos; Suzie L Miller; Charles C Roehr; Georg M Schmölzer; Peter G Davis; Timothy J M Moss; Domenic A LaRosa; Stuart B Hooper; Graeme R Polglase
Journal:  Front Pediatr       Date:  2015-11-10       Impact factor: 3.418

  3 in total

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