Literature DB >> 2464545

Effect of recombinant interleukin-1 on mRNA levels in rat liver.

F A De Jong1, H E Birch, G Schreiber.   

Abstract

Levels of rat liver mRNA for the plasma proteins albumin, apolipoprotein E, transthyretin, transferrin, alpha 1-acid glycoprotein, major acute-phase alpha 1-protein, and the beta-chain of fibrinogen were measured after intraperitoneal injection of interleukin-1 alpha (IL-1). A maximum response of mRNA levels for most of the plasma proteins studied was reached between 6 and 10 h after injection of IL-1. The results suggest that at the dosage used, IL-1 alone does not elicit a typical acute-phase response of the plasma protein-synthesizing system of the liver.

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Year:  1988        PMID： 2464545     DOI： 10.1007/bf00914322

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  13 in total

1.  Effect of leukocytic endogenous mediator on C-reactive protein in rabbits.

Authors:  C R Merriman; L A Pulliam; R F Kampschmidt
Journal:  Proc Soc Exp Biol Med       Date:  1975-07

2.  Murine interleukin 1 stimulates alpha 2-macroglobulin synthesis in rat hepatocyte primary cultures.

Authors:  J Bauer; W Weber; T A Tran-Thi; G H Northoff; K Decker; W Gerok; P C Heinrich
Journal:  FEBS Lett       Date:  1985-10-14       Impact factor: 4.124

3.  Levels of messenger ribonucleic acids for plasma proteins in rat liver during acute experimental inflammation.

Authors:  G Schreiber; A R Aldred; T Thomas; H E Birch; P W Dickson; G F Tu; P C Heinrich; W Northemann; G J Howlett; F A de Jong
Journal:  Inflammation       Date:  1986-03       Impact factor: 4.092

4.  Effect of leukocytic endogenous mediator on plasma fibrinogen and haptoglobin.

Authors:  R F Kampschmidt; H F Upchurch
Journal:  Proc Soc Exp Biol Med       Date:  1974-07

5.  The effects of leucocytic and serum factors on fibrinogen biosynthesis in cultured hepatocytes.

Authors:  R G Rupp; G M Fuller
Journal:  Exp Cell Res       Date:  1979-01       Impact factor: 3.905

Review 6.  The numerous postulated biological manifestations of interleukin-1.

Authors:  R F Kampschmidt
Journal:  J Leukoc Biol       Date:  1984-09       Impact factor: 4.962

7.  Effects of leukocytic endogenous mediator on hemopexin, transferr, and liver catalase.

Authors:  C R Merriman; H F Upchurch; R F Kampschmidt
Journal:  Proc Soc Exp Biol Med       Date:  1978-04

8.  Rat transthyretin (prealbumin). Molecular cloning, nucleotide sequence, and gene expression in liver and brain.

Authors:  P W Dickson; G J Howlett; G Schreiber
Journal:  J Biol Chem       Date:  1985-07-05       Impact factor: 5.157

9.  Identification and partial characterization of hepatocyte-stimulating factor from leukemia cell lines: comparison with interleukin 1.

Authors:  B M Woloski; G M Fuller
Journal:  Proc Natl Acad Sci U S A       Date:  1985-03       Impact factor: 11.205

10.  Monocyte-conditioned medium, interleukin-1, and tumor necrosis factor stimulate the acute phase response in human hepatoma cells in vitro.

Authors:  G J Darlington; D R Wilson; L B Lachman
Journal:  J Cell Biol       Date:  1986-09       Impact factor: 10.539
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  3 in total

1.  In vivo changes in plasma acute phase protein levels in the rat induced by slow release of IL-1, IL-6 and TNF.

Authors:  E J Lewis; A D Sedgwick; T H Hanahoe
Journal:  Mediators Inflamm       Date:  1992       Impact factor: 4.711

2.  Acute phase protein response and polymorphonuclear leukocyte cathepsin g release after slow interleukin-1 stimulation in the rat.

Authors:  P Björk; T Gudmundsson; K Ohlsson
Journal:  Mediators Inflamm       Date:  1994       Impact factor: 4.711

3.  Differential Proliferative Characteristics of Alveolar Fibroblasts in Interstitial Lung Diseases: Regulative Role of IL-1 and PGE(2).

Authors:  E Fireman; S Ben Efraim; J Greif; H Peretz; S Kivity; M Topilsky; Y Rodrig; A Yellin; R N Apte
Journal:  Mediators Inflamm       Date:  1994       Impact factor: 4.711
  3 in total

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