Muhammed Mubarak1, Hamid Nasri2. 1. Department of Histopathology, Sindh Institute of Urology and Transplantation (SIUT), Karachi, Pakistan. 2. Department of Nephrology, Division of Nephropathology, Isfahan University of Medical Sciences, Isfahan, Iran.
Abstract
CONTEXT: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder which commonly affects kidneys. EVIDENCE ACQUISITIONS: Directory of Open Access Journals (DOAJ), Google Scholar, PubMed (NLM), LISTA (EBSCO) and Web of Science have been searched. RESULTS: There is sufficient epidemiological, clinical and histopathological evidence to show that antiphospholipid syndrome is a distinctive lesion caused by antiphospholipid antibodies in patients with different forms of antiphospholipid syndrome. It is now time to devise a classification for an accurate diagnosis and prognostication of the disease. CONCLUSIONS: Now that the morphological lesions of APSN are sufficiently well characterized, it is prime time to devise a classification which is of diagnostic and prognostic utility in this disease.
CONTEXT: Antiphospholipid syndrome (APS) is a systemic autoimmune disorder which commonly affects kidneys. EVIDENCE ACQUISITIONS: Directory of Open Access Journals (DOAJ), Google Scholar, PubMed (NLM), LISTA (EBSCO) and Web of Science have been searched. RESULTS: There is sufficient epidemiological, clinical and histopathological evidence to show that antiphospholipid syndrome is a distinctive lesion caused by antiphospholipid antibodies in patients with different forms of antiphospholipid syndrome. It is now time to devise a classification for an accurate diagnosis and prognostication of the disease. CONCLUSIONS: Now that the morphological lesions of APSN are sufficiently well characterized, it is prime time to devise a classification which is of diagnostic and prognostic utility in this disease.
Authors: Eric Daugas; Dominique Nochy; Du Le Thi Huong; Pierre Duhaut; Hélène Beaufils; Valérie Caudwell; Jean Bariety; Jean-Charles Piette; Gary Hill Journal: J Am Soc Nephrol Date: 2002-01 Impact factor: 10.121