Literature DB >> 24643707

Selective homocysteine turn-on fluorescent probes and their bioimaging applications.

Hye Yeon Lee1, Yoon Pyo Choi, Sunkyung Kim, Taejin Yoon, Zhiqian Guo, Songyi Lee, K M K Swamy, Gyoungmi Kim, Jin Yong Lee, Injae Shin, Juyoung Yoon.   

Abstract

The design and development of new pyrene-based fluorescent probes, P-Hcy-1 and P-Hcy-2, which display selective fluorescence enhancements in response to homocysteine (Hcy), are described. The distinctly different fluorescence responses of P-Hcy-1 and P-Hcy-2 to Hcy vs. Cys are explained by theoretical calculations. Finally, the results of cell experiments show that these probes can be used to selectively detect Hcy in mammalian cells.

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Year:  2014        PMID： 24643707     DOI： 10.1039/c4cc00243a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  11 in total

1.  Fluorescein Tri-Aldehyde Promotes the Selective Detection of Homocysteine.

Authors:  Aabha Barve; Mark Lowry; Jorge O Escobedo; Josephrajan Thainashmuthu; Robert M Strongin
Journal:  J Fluoresc       Date:  2016-01-16       Impact factor: 2.217

Review 2.  Fluorescent Probes with Multiple Binding Sites for the Discrimination of Cys, Hcy, and GSH.

Authors:  Cai-Xia Yin; Kang-Ming Xiong; Fang-Jun Huo; James C Salamanca; Robert M Strongin
Journal:  Angew Chem Int Ed Engl       Date:  2017-09-22       Impact factor: 15.336

3.  pH-Dependent Fluorescent Probe That Can Be Tuned for Cysteine or Homocysteine.

Authors:  Yongkang Yue; Fangjun Huo; Xiaoqi Li; Ying Wen; Tao Yi; James Salamanca; Jorge O Escobedo; Robert M Strongin; Caixia Yin
Journal:  Org Lett       Date:  2016-12-20       Impact factor: 6.005

Review 4.  Molecular Probes, Chemosensors, and Nanosensors for Optical Detection of Biorelevant Molecules and Ions in Aqueous Media and Biofluids.

Authors:  Joana Krämer; Rui Kang; Laura M Grimm; Luisa De Cola; Pierre Picchetti; Frank Biedermann
Journal:  Chem Rev       Date:  2022-01-07       Impact factor: 60.622

5.  Coumarin-based fluorescent 'AND' logic gate probes for the detection of homocysteine and a chosen biological analyte.

Authors:  Luling Wu; Jordan E Gardiner; Lokesh K Kumawat; Hai-Hao Han; Ruiying Guo; Xin Li; Xiao-Peng He; Robert B P Elmes; Adam C Sedgwick; Steven D Bull; Tony D James
Journal:  RSC Adv       Date:  2019-08-27       Impact factor: 4.036

6.  Preparation of a cyanine-based fluorescent probe for highly selective detection of glutathione and its use in living cells and tissues of mice.

Authors:  Jun Yin; Younghee Kwon; Dabin Kim; Dayoung Lee; Gyoungmi Kim; Ying Hu; Ji-Hwan Ryu; Juyoung Yoon
Journal:  Nat Protoc       Date:  2015-10-15       Impact factor: 13.491

Review 7.  Fluorescent Chemosensors for Various Analytes Including Reactive Oxygen Species, Biothiol, Metal Ions, and Toxic Gases.

Authors:  Nahyun Kwon; Ying Hu; Juyoung Yoon
Journal:  ACS Omega       Date:  2018-10-19

Review 8.  The chronological evolution of small organic molecular fluorescent probes for thiols.

Authors:  Yongkang Yue; Fangjun Huo; Caixia Yin
Journal:  Chem Sci       Date:  2020-12-15       Impact factor: 9.825

Review 9.  Recent Progress in Fluorescent Imaging Probes.

Authors:  Yen Leng Pak; K M K Swamy; Juyoung Yoon
Journal:  Sensors (Basel)       Date:  2015-09-22       Impact factor: 3.576

10.  Synthesis and Application of an Aldazine-Based Fluorescence Chemosensor for the Sequential Detection of Cu²⁺ and Biological Thiols in Aqueous Solution and Living Cells.

Authors:  Hongmin Jia; Ming Yang; Qingtao Meng; Guangjie He; Yue Wang; Zhizhi Hu; Run Zhang; Zhiqiang Zhang
Journal:  Sensors (Basel)       Date:  2016-01-11       Impact factor: 3.576
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