Literature DB >> 24643239

Drug discovery: follow your lead.

Brian K Shoichet1.   

Abstract

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Year:  2014        PMID: 24643239     DOI: 10.1038/nchembio.1484

Source DB:  PubMed          Journal:  Nat Chem Biol        ISSN: 1552-4450            Impact factor:   15.040


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  6 in total

1.  Reflections on drug research.

Authors:  James Black
Journal:  Br J Pharmacol       Date:  2010-11       Impact factor: 8.739

Review 2.  Selective optimization of side activities: the SOSA approach.

Authors:  Camille G Wermuth
Journal:  Drug Discov Today       Date:  2006-02       Impact factor: 7.851

3.  Unexpected nanomolar inhibition of carbonic anhydrase by COX-2-selective celecoxib: new pharmacological opportunities due to related binding site recognition.

Authors:  Alexander Weber; Angela Casini; Andreas Heine; Daniel Kuhn; Claudiu T Supuran; Andrea Scozzafava; Gerhard Klebe
Journal:  J Med Chem       Date:  2004-01-29       Impact factor: 7.446

4.  A pharmacological organization of G protein-coupled receptors.

Authors:  Henry Lin; Maria F Sassano; Bryan L Roth; Brian K Shoichet
Journal:  Nat Methods       Date:  2013-01-06       Impact factor: 28.547

5.  Selective inhibition of BET bromodomains.

Authors:  Panagis Filippakopoulos; Jun Qi; Sarah Picaud; Yao Shen; William B Smith; Oleg Fedorov; Elizabeth M Morse; Tracey Keates; Tyler T Hickman; Ildiko Felletar; Martin Philpott; Shonagh Munro; Michael R McKeown; Yuchuan Wang; Amanda L Christie; Nathan West; Michael J Cameron; Brian Schwartz; Tom D Heightman; Nicholas La Thangue; Christopher A French; Olaf Wiest; Andrew L Kung; Stefan Knapp; James E Bradner
Journal:  Nature       Date:  2010-09-24       Impact factor: 49.962

6.  Dual kinase-bromodomain inhibitors for rationally designed polypharmacology.

Authors:  Pietro Ciceri; Susanne Müller; Alison O'Mahony; Oleg Fedorov; Panagis Filippakopoulos; Jeremy P Hunt; Elisabeth A Lasater; Gabriel Pallares; Sarah Picaud; Christopher Wells; Sarah Martin; Lisa M Wodicka; Neil P Shah; Daniel K Treiber; Stefan Knapp
Journal:  Nat Chem Biol       Date:  2014-03-02       Impact factor: 15.040

  6 in total
  1 in total

1.  Parallel worlds of public and commercial bioactive chemistry data.

Authors:  Christopher A Lipinski; Nadia K Litterman; Christopher Southan; Antony J Williams; Alex M Clark; Sean Ekins
Journal:  J Med Chem       Date:  2014-12-04       Impact factor: 7.446

  1 in total

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