Levent Küçük1, Burçin Keçeci2, Dündar Sabah2, Güven Yücetürk2. 1. Department of Orthopedics and Traumatology, Ege University Faculty of Medicine, İzmir, Turkey. kucuklevent@yahoo.com. 2. Department of Orthopedics and Traumatology, Ege University Faculty of Medicine, İzmir, Turkey.
Abstract
OBJECTIVE: The aim of this study was to evaluate the results of surgical treatment of aggressive fibromatosis and the effects of prognostic factors on recurrence. METHODS: Forty patients (24 female, 16 male; average age: 31.2 years) diagnosed with aggressive fibromatosis were evaluated retrospectively. Nine patients with tumor-positive surgical margins macroscopically were excluded. Prognostic factors such as age, gender, localization, admission status, compartment status, surgical margin, tumor size and adjuvant radiotherapy were evaluated. RESULTS: Recurrence rate was 29%. Average disease free survival was 46±4 months. There was no statistically significant relation between prognostic factors and recurrence. Clinical results of the patients receiving adjuvant radiotherapy were more satisfactory. CONCLUSION: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.
OBJECTIVE: The aim of this study was to evaluate the results of surgical treatment of aggressive fibromatosis and the effects of prognostic factors on recurrence. METHODS: Forty patients (24 female, 16 male; average age: 31.2 years) diagnosed with aggressive fibromatosis were evaluated retrospectively. Nine patients with tumor-positive surgical margins macroscopically were excluded. Prognostic factors such as age, gender, localization, admission status, compartment status, surgical margin, tumor size and adjuvant radiotherapy were evaluated. RESULTS: Recurrence rate was 29%. Average disease free survival was 46±4 months. There was no statistically significant relation between prognostic factors and recurrence. Clinical results of the patients receiving adjuvant radiotherapy were more satisfactory. CONCLUSION: Adjuvant radiotherapy administration appears to be a rational treatment method instead of sacrificing function to achieve wide surgical margins.
Authors: Firouzeh Kamali; Wei-Lien Wang; B A Guadagnolo; Patricia S Fox; Valerae O Lewis; Alexander J Lazar; Anthony P Conley; Vinod Ravi; Mohammad Toliyat; Harshad S Ladha; Brian P Hobbs; Behrang Amini Journal: Br J Radiol Date: 2015-11-18 Impact factor: 3.039