Literature DB >> 24643074

Corneal crystalline deposits associated with topically applied gatifloxacin.

Maxwell Elia1, Sarah Khodadadeh, Jessica Chow.   

Abstract

PURPOSE: To report a case of corneal crystalline deposits from the use of gatifloxacin 0.5% topical antibiotic after combined cataract extraction and trabeculotomy ab interno surgery.
METHODS: A 59-year-old woman presented after combined cataract extraction and trabeculotomy ab interno with crystalline deposits in the anterior corneal stroma. Clinical examination and slit-lamp photography were performed.
RESULTS: The slit-lamp examination showed inferior white crystal deposition in the anterior stroma with overlying punctate epithelial erosions 4 weeks postoperatively. The eye was asymptomatic, but the deposition was cosmetically noticeable to the patient. Serial slit-lamp photography demonstrated resolution of the crystalline deposits 30 days after the discontinuation of eye drops.
CONCLUSIONS: The authors present a rare case of stromal crystallization from topical gatifloxacin treatment. Complete resolution of corneal deposits was seen 30 days after the discontinuation of the drops without sequelae.

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Year:  2014        PMID: 24643074     DOI: 10.1097/ICO.0000000000000101

Source DB:  PubMed          Journal:  Cornea        ISSN: 0277-3740            Impact factor:   2.651


  2 in total

1.  Corneal deposition of fluoroquinolones after penetrating keratoplasty: case series.

Authors:  Sanjeeta Sitaula; Sanjay K Singh
Journal:  Int Med Case Rep J       Date:  2019-05-08

Review 2.  Drug-induced corneal deposits: an up-to-date review.

Authors:  Jean-Yves Sahyoun; Saama Sabeti; Marie-Claude Robert
Journal:  BMJ Open Ophthalmol       Date:  2022-03-25
  2 in total

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