Literature DB >> 24642585

Vocal process granulomas: a systematic review of treatment.

Petros D Karkos1, Michael George, Jan Van Der Veen, Helen Atkinson, Raghav C Dwivedi, Dae Kim, Costa Repanos.   

Abstract

OBJECTIVES: Vocal process granulomas (VPGs) are benign laryngeal lesions with controversial treatment and a tendency to recur. There are several treatment options with unpredictable results, high recurrence rates, and disappointing long-term outcome. The aims of this article are to focus on evidence-based current treatment strategies for primary lesions and recurrences. DATA SOURCES: The data came from a systematic review of the literature.
METHODS: Main outcome measures were recurrence rate, reduction, and/or complete resolution. Inclusion criteria included English literature, randomized and nonrandomized trials, prospective and retrospective studies, and primary and recurrent cases. Exclusion criteria included case reports, teaching reviews, and papers not focusing on treatment.
RESULTS: The time frame of the included studies was from 1997 to 2012. There are 6 different treatment options (single or combined) for VPG. Antireflux medication is the mainstay treatment and when combined with lifestyle changes and voice therapy results in the lowest recurrence rate. "Bloodless" in-office or in-theater laser techniques appear to have lower recurrence rates when compared to traditional cold steel microlaryngoscopy techniques, especially for recurrences.
CONCLUSIONS: There is level 2A evidence that antireflux treatment is the main treatment strategy for vocal process granulomas with surgery reserved only for failures of medical treatment or airway obstruction or when diagnosis is in doubt.

Entities:  

Keywords:  antireflux treatment; benign; gastroesophageal reflux; larynx; laser; lesions; proton pump inhibitors; recurrence; resolution; speech therapy; vocal process granulomas

Mesh:

Substances:

Year:  2014        PMID: 24642585     DOI: 10.1177/0003489414525921

Source DB:  PubMed          Journal:  Ann Otol Rhinol Laryngol        ISSN: 0003-4894            Impact factor:   1.547


  9 in total

1.  Ideal Particle Sizes for Inhaled Steroids Targeting Vocal Granulomas: Preliminary Study Using Computational Fluid Dynamics.

Authors:  Elizabeth L Perkins; Saikat Basu; Guilherme J M Garcia; Robert A Buckmire; Rupali N Shah; Julia S Kimbell
Journal:  Otolaryngol Head Neck Surg       Date:  2017-11-21       Impact factor: 3.497

2.  Laryngeal Contact Ulcer.

Authors:  Benjamin G Barrena; Tanner M Miller; Brenda L Nelson
Journal:  Head Neck Pathol       Date:  2020-05-07

3.  Reflux and Voice Disorders: Have We Established Causality?

Authors:  G Todd Schneider; Michael F Vaezi; David O Francis
Journal:  Curr Otorhinolaryngol Rep       Date:  2016-07-09

4.  Laryngeal granuloma occurring after surgery for laryngeal cancer treated by surgical removal and immediate post-operative radiotherapy: A case report.

Authors:  Jingyi Wu; Tongchao Jiang; Yu Wu; Lijuan Ding; Lihua Dong
Journal:  Medicine (Baltimore)       Date:  2019-09       Impact factor: 1.817

5.  Pediatric bilateral vocal cord granulomas presenting as airway foreign body following prolonged intubation due to COVID-19 related multisystem inflammatory syndrome.

Authors:  Viraj N Shah; Neeraj V Suresh; Luke J Pasick; Michael K Ghiam; Leonardo A Torres
Journal:  Otolaryngol Case Rep       Date:  2021-04-27

6.  Laryngeal granulomas in patients after two-jaw surgery - Four cases report.

Authors:  Jae Gyok Song; Won Ho Cho; Sung Mi Ji; Jeong Heon Park; Seok Kon Kim
Journal:  Anesth Pain Med (Seoul)       Date:  2019-10-31

7.  Bilateral vocal fold granulomas following double-lumen endotracheal tube placement.

Authors:  Sarang S Koushik; David G Lott; Harish Ramakrishna
Journal:  J Anaesthesiol Clin Pharmacol       Date:  2017 Jul-Sep

8.  Vocal cord granuloma after transoral thyroidectomy using oral endotracheal intubation: two case reports.

Authors:  Tsung-Jung Liang; Nai-Yu Wang; Shiuh-Inn Liu; I-Shu Chen
Journal:  BMC Anesthesiol       Date:  2021-06-14       Impact factor: 2.217

Review 9.  Treatment of post-intubation laryngeal granulomas: systematic review and proportional meta-analysis.

Authors:  Caroline Fernandes Rimoli; Regina Helena Garcia Martins; Daniele Cristina Catâneo; Rui Imamura; Antonio José Maria Catâneo
Journal:  Braz J Otorhinolaryngol       Date:  2018-04-14
  9 in total

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