Literature DB >> 24639235

Patient demographics and health plan paid costs in chronic inflammatory demyelinating polyneuropathy.

Jeffrey T Guptill1, Mark B Bromberg, Li Zhu, Bal K Sharma, Amy R Thompson, Andrew Krueger, Donald B Sanders.   

Abstract

INTRODUCTION: We determined health plan paid costs and healthcare resource usage of patients with chronic inflammatory demyelinating polyneuropathy (CIDP).
METHODS: CIDP patients from 9 U.S. commercial health plans with claims in 2011 were identified from the Accordant Health Services claims database. We examined demographics, prevalence of comorbidities, prescribed drugs, place of service, and mean annual health plan paid costs per patient.
RESULTS: From 6.5 million covered lives, 73 (56% men; mean age 47) met study entry criteria. The most prescribed therapies were intravenous immunoglobulin (IVIg) (26% of patients), gabapentin (26%), and prednisone (16%). The annual health plan paid cost was $56,953. Pharmacy cost was the major cost driver (57% of the total), and IVIg totaled 90% of the pharmacy costs.
CONCLUSIONS: Healthcare costs for CIDP patients are substantial, with a large burden in pharmacy usage. Studies are needed to determine optimal long-term treatment strategies for CIDP, particularly related to IVIg.
Copyright © 2013 Wiley Periodicals, Inc.

Entities:  

Keywords:  CIDP; chronic inflammatory polyradiculoneuropathy; cost analysis; costs; health care cost; intravenous immune globulin

Mesh:

Substances:

Year:  2014        PMID: 24639235     DOI: 10.1002/mus.24109

Source DB:  PubMed          Journal:  Muscle Nerve        ISSN: 0148-639X            Impact factor:   3.217


  8 in total

1.  Progress in Recognizing and Treating Polyneuropathy.

Authors:  Bernd C Kieseier; Hans-Peter Hartung
Journal:  Dtsch Arztebl Int       Date:  2018-02-09       Impact factor: 5.594

2.  Incidence and Prevalence of Chronic Inflammatory Demyelinating Polyradiculoneuropathy: A Systematic Review and Meta-Analysis.

Authors:  Merel C Broers; Carina Bunschoten; Daan Nieboer; Hester F Lingsma; Bart C Jacobs
Journal:  Neuroepidemiology       Date:  2019-01-22       Impact factor: 3.282

3.  Treatment Patterns and Costs of Chronic Inflammatory Demyelinating Polyneuropathy: A Claims Database Analysis.

Authors:  Jeffrey T Guptill; M Chris Runken; Michael Eaddy; Orsolya Lunacsek; Rupali M Fuldeore
Journal:  Am Health Drug Benefits       Date:  2019-05

4.  The Cost Effectiveness of Immunoglobulin vs. Hematopoietic Stem Cell Transplantation for CIDP.

Authors:  Richard K Burt; Paul Tappenden; Roumen Balabanov; Xiaoqiang Han; Kathleen Quigley; John A Snowden; Basil Sharrack
Journal:  Front Neurol       Date:  2021-03-22       Impact factor: 4.003

Review 5.  Expanding the Role of the Pharmacist: Immunoglobulin Therapy and Disease Management in Neuromuscular Disorders.

Authors:  Eric M Tichy; Barbara Prosser; Drew Doyle
Journal:  J Pharm Pract       Date:  2020-07-17

6.  The economic burden of CIDP in the United States: A case-control study.

Authors:  Victoria Divino; Rajiv Mallick; Mitch DeKoven; Girishanthy Krishnarajah
Journal:  PLoS One       Date:  2018-10-23       Impact factor: 3.240

Review 7.  The Misdiagnosis of CIDP: A Review.

Authors:  Jeffrey A Allen
Journal:  Neurol Ther       Date:  2020-03-26

Review 8.  Systematic literature review of burden of illness in chronic inflammatory demyelinating polyneuropathy (CIDP).

Authors:  Luis Querol; M Crabtree; M Herepath; E Priedane; I Viejo Viejo; S Agush; P Sommerer
Journal:  J Neurol       Date:  2020-06-24       Impact factor: 4.849

  8 in total

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