Literature DB >> 24639091

Biocatalytic synthesis of optically active hydroxyesters via lipase-catalyzed decarboxylative aldol reaction and kinetic resolution.

Wei-Wei Zhang1, Na Wang, Xing-Wen Feng, Yang Zhang, Xiao-Qi Yu.   

Abstract

A two-step sequential biocatalytic process for the synthesis of chiral hydroxyesters that combines a lipase-catalyzed decarboxylative aldol reaction followed by kinetic resolution has been developed. The excellent combination of conventional and unconventional functions provides an attractive route for expanding the applications of biocatalysis.

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Year:  2014        PMID： 24639091     DOI： 10.1007/s12010-014-0860-z

Source DB:  PubMed          Journal:  Appl Biochem Biotechnol        ISSN： 0273-2289            Impact factor:   2.926


  3 in total

1.  High enantioselective Novozym 435-catalyzed esterification of (R,S)-flurbiprofen monitored with a chiral stationary phase.

Authors:  Tomasz Siódmiak; Debby Mangelings; Yvan Vander Heyden; Marta Ziegler-Borowska; Michał Piotr Marszałł
Journal:  Appl Biochem Biotechnol       Date:  2015-01-06       Impact factor: 2.926

2.  Biocatalytic decarboxylative Michael addition for synthesis of 1,4-benzoxazinone derivatives.

Authors:  Hossein Bavandi; Mansour Shahedi; Zohreh Habibi; Maryam Yousefi; Jesper Brask; Mehdi Mohammadi
Journal:  Sci Rep       Date:  2022-07-26       Impact factor: 4.996

3.  CALB Immobilized onto Magnetic Nanoparticles for Efficient Kinetic Resolution of Racemic Secondary Alcohols: Long-Term Stability and Reusability.

Authors:  Xiu Xing; Jun-Qi Jia; Jing-Fan Zhang; Zi-Wen Zhou; Jun Li; Na Wang; Xiao-Qi Yu
Journal:  Molecules       Date:  2019-01-30       Impact factor: 4.411
  3 in total

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