Literature DB >> 24634882

Regulation of scleral fibroblast differentiation by bone morphogenetic protein-2.

Hong-Hui Li1, Li-Jun Huo1, Zhen-Ya Gao1, Feng Zhao1, Jun-Wen Zeng1.   

Abstract

Bone morphogenesis proteins (BMPs) are multi-functional growth factors. They are expressed in retina, retinal pigment epithelium (RPE) and sclera and serve as a regulator in the growth and development of the eye. This article reviewed the chondrogenic potency of the sclera, biochemical and pathological changes of myopic scleral tissue and the differentiation of chondrogenesis by BMP-2. We proposed the hypothesis that BMP-2 can regulate differentiate of scleral fibroblasts and affect the development of myopia.

Entities:  

Keywords:  bone morphogenetic protein-2; myopia; sclera

Year:  2014        PMID： 24634882      PMCID： PMC3949477          DOI： 10.3980/j.issn.2222-3959.2014.01.28

Source DB:  PubMed          Journal:  Int J Ophthalmol        ISSN： 2222-3959            Impact factor:   1.779


  40 in total

1.  Chondrogenic differentiation of neonatal human dermal fibroblasts encapsulated in alginate beads with hydrostatic compression under hypoxic conditions in the presence of bone morphogenetic protein-2.

Authors:  Milind Singh; Mallory Pierpoint; Antonios G Mikos; F Kurtis Kasper
Journal:  J Biomed Mater Res A       Date:  2011-05-31       Impact factor: 4.396

Review 2.  Biomechanics of the sclera in myopia: extracellular and cellular factors.

Authors:  Neville A McBrien; Andrew I Jobling; Alex Gentle
Journal:  Optom Vis Sci       Date:  2009-01       Impact factor: 1.973

3.  Induction of chondrogenic differentiation in cultured fibroblasts isolated from the inferior turbinate.

Authors:  Sung Won Kim; Jin Hee Cho; Myung Wha Hong; Jong-Won Rhie; He Ro Yoon
Journal:  Otolaryngol Head Neck Surg       Date:  2008-07       Impact factor: 3.497

Review 4.  The sclera and myopia.

Authors:  Jody A Summers Rada; Setareh Shelton; Thomas T Norton
Journal:  Exp Eye Res       Date:  2005-10-03       Impact factor: 3.467

5.  Scleral remodeling during the development of and recovery from axial myopia in the tree shrew.

Authors:  N A McBrien; P Lawlor; A Gentle
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-11       Impact factor: 4.799

6.  Induced myopia associated with increased scleral creep in chick and tree shrew eyes.

Authors:  J R Phillips; M Khalaj; N A McBrien
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-07       Impact factor: 4.799

7.  Bone morphogenetic proteins-2 and -4: negative growth regulators in adult retinal pigmented epithelium.

Authors:  J R Mathura; N Jafari; J T Chang; S F Hackett; K J Wahlin; N G Della; N Okamoto; D J Zack; P A Campochiaro
Journal:  Invest Ophthalmol Vis Sci       Date:  2000-02       Impact factor: 4.799

8.  A requirement for bone morphogenetic protein-7 during development of the mammalian kidney and eye.

Authors:  A T Dudley; K M Lyons; E J Robertson
Journal:  Genes Dev       Date:  1995-11-15       Impact factor: 11.361

9.  Effects of imposed defocus of opposite sign on temporal gene expression patterns of BMP4 and BMP7 in chick RPE.

Authors:  Yan Zhang; Yue Liu; Carol Ho; Christine F Wildsoet
Journal:  Exp Eye Res       Date:  2013-02-19       Impact factor: 3.467

10.  Prevention of collagen crosslinking increases form-deprivation myopia in tree shrew.

Authors:  N A McBrien; T T Norton
Journal:  Exp Eye Res       Date:  1994-10       Impact factor: 3.467
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  3 in total

1.  Assessment of expressions of Bcl-XL, b-FGF, Bmp-2, Caspase-3, PDGFR-α, Smad1 and TGF-β1 genes in a rat model of lung ischemia/reperfusion.

Authors:  Hasan Şimşek; Şeniz Demiryürek; Tuncer Demir; Hüsne Didem Atabay; Ali Osman Çeribasi; Recep Bayraktar; Davut Sinan Kaplan; Serdar Öztuzcu; Beyhan Cengiz
Journal:  Iran J Basic Med Sci       Date:  2016-02       Impact factor: 2.699

2.  RNA sequence analysis identified bone morphogenetic protein-2 (BMP2) as a biomarker underlying form deprivation myopia.

Authors:  Chun-Wen Chen; Jing-Yan Yao
Journal:  Biochem Biophys Rep       Date:  2022-04-18

3.  Systematic Analysis of Transcriptomic Profile of the Effects of Low Dose Atropine Treatment on Scleral Fibroblasts using Next-Generation Sequencing and Bioinformatics.

Authors:  Yu-Ting Hsiao; Wei-An Chang; Ming-Tse Kuo; Jung Lo; Hsien-Chung Lin; Meng-Chi Yen; Shu-Fang Jian; Yi-Jen Chen; Po-Lin Kuo
Journal:  Int J Med Sci       Date:  2019-11-09       Impact factor: 3.738
  3 in total

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