Literature DB >> 24633067

Women's perspective: intra-detrusor botox versus sacral neuromodulation for overactive bladder symptoms after unsuccessful anticholinergic treatment.

Pooja Balchandra1, Lynne Rogerson.   

Abstract

INTRODUCTION AND HYPOTHESIS: Comprehension of women's perspective and reasons for their choice between intra-detrusor botox (botox) and sacral neuromodulation (SNM) after failed anticholinergic treatment for overactive bladder syndrome (OAB) have not been evaluated and reported in the literature. Our voluntary service evaluation survey aimed to determine reasons behind individual patient choice.
METHODS: All women were counseled in detail regarding the two treatment options available after failed anticholinergic treatment as per the hospital trust policy. Once the decision-making process was completed, they were asked to highlight one or more of the 12 questions within the survey that influenced their decision-making process.
RESULTS: Fifty patients, with a mean age of 61.66 years (range 38-82 years) participated in our voluntary survey. Seventy-four per cent chose Botox and 26% chose SNM. In the botox group 54.05% disliked the thought of a foreign body in the back with SNM; 45.94% quoted shorter waiting times and 43.24% said that the quicker onset of benefit (within 3-5 days) with botox compared with SNM (up to 2 weeks) helped to influence their decision towards botox. In the SNM group 61.53% were averse to the potential need for botox to be repeated at variable intervals; 46.15% chose SNM to avoid the risk of urinary retention associated with botox.
CONCLUSION: The botox group seemed more likely to need quicker results with easy access to the treatment modality, whilst the SNM group seemed keener to focus on a more permanent option with a known interval for the repeat procedure. The difference in patient choice was found to be statistically significant.

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Year:  2014        PMID: 24633067     DOI: 10.1007/s00192-014-2360-7

Source DB:  PubMed          Journal:  Int Urogynecol J        ISSN: 0937-3462            Impact factor:   2.894


  13 in total

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Authors:  Apostolos Apostolidis
Journal:  Neurourol Urodyn       Date:  2011-06       Impact factor: 2.696

Review 2.  Management of refractory overactive bladder.

Authors:  I Giarenis; L Cardozo
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3.  Cost-effectiveness of sacral neuromodulation compared to botulinum neurotoxin a or continued medical management in refractory overactive bladder.

Authors:  Salvador Arlandis; David Castro; Carlos Errando; Eldiberto Fernández; Miguel Jiménez; Paloma González; Carlos Crespo; Funke Staeuble; José Manuel Rodríguez; Max Brosa
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4.  Efficacy and safety of onabotulinumtoxinA for idiopathic overactive bladder: a double-blind, placebo controlled, randomized, dose ranging trial.

Authors:  Roger Dmochowski; Christopher Chapple; Victor W Nitti; Michael Chancellor; Karel Everaert; Catherine Thompson; Grace Daniell; Jihao Zhou; Cornelia Haag-Molkenteller
Journal:  J Urol       Date:  2010-10-16       Impact factor: 7.450

5.  The role of neuromodulation in the management of urinary urge incontinence.

Authors:  P Abrams; J G Blaivas; C J Fowler; J L Fourcroy; S A Macdiarmid; S W Siegel; P Van Kerrebroeck
Journal:  BJU Int       Date:  2003-03       Impact factor: 5.588

6.  Does sacral nerve stimulation improve global pelvic function in women?

Authors:  A M Jadav; H Wadhawan; G L Jones; L W Wheldon; S C Radley; S R Brown
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7.  Battery explantation after sacral neuromodulation in the Medicare population.

Authors:  Anne P Cameron; Jennifer T Anger; Rodger Madison; Christopher S Saigal; J Quentin Clemens
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8.  OnabotulinumtoxinA 100 U significantly improves all idiopathic overactive bladder symptoms and quality of life in patients with overactive bladder and urinary incontinence: a randomised, double-blind, placebo-controlled trial.

Authors:  Christopher Chapple; Karl-Dietrich Sievert; Scott MacDiarmid; Vik Khullar; Piotr Radziszewski; Christopher Nardo; Catherine Thompson; Jihao Zhou; Cornelia Haag-Molkenteller
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Review 9.  Sacral neuromodulation and intravesical botulinum toxin for refractory overactive bladder.

Authors:  Kelly Kantartzis; Jonathan Shepherd
Journal:  Curr Opin Obstet Gynecol       Date:  2012-10       Impact factor: 1.927

10.  Early effect on the overactive bladder symptoms following botulinum neurotoxin type A injections for detrusor overactivity.

Authors:  Vinay Kalsi; Apostolos Apostolidis; Gwen Gonzales; Sohier Elneil; Prokar Dasgupta; Clare J Fowler
Journal:  Eur Urol       Date:  2007-12-26       Impact factor: 20.096

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  8 in total

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2.  [Sacral neuromodulation for refractory overactive bladder].

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3.  Patient preferences for treating refractory overactive bladder in the UK.

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4.  Patient treatment preferences for symptomatic refractory urodynamic idiopathic detrusor overactivity.

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Journal:  Urol Ann       Date:  2017 Jul-Sep

5.  Urinary retention in female OAB after intravesical Botox injection: who is really at risk?

Authors:  Pawel Miotla; Rufus Cartwright; Katarzyna Skorupska; Michal Bogusiewicz; Ewa Markut-Miotla; Konrad Futyma; Tomasz Rechberger
Journal:  Int Urogynecol J       Date:  2016-11-26       Impact factor: 2.894

6.  Initial clinical experience with selective bladder denervation for refractory overactive bladder.

Authors:  Le Mai Tu; Stefan De Wachter; Magali Robert; Roger R Dmochowski; Larry E Miller; Karel Everaert
Journal:  Neurourol Urodyn       Date:  2018-11-29       Impact factor: 2.696

7.  Eight-Year Experience With Botulinum Toxin Type-A Injections for the Treatment of Nonneurogenic Overactive Bladder: Are Repeated Injections Worthwhile?

Authors:  Shannon Hk Kim; David Habashy; Sana Pathan; Vincent Tse; Ruth Collins; Lewis Chan
Journal:  Int Neurourol J       Date:  2016-03-16       Impact factor: 2.835

Review 8.  Neuromodulation - a therapeutic option for refractory overactive bladder. A recent literature review.

Authors:  Jacek K Szymański; Aneta Słabuszewska-Jóźwiak; Kornelia Zaręba; Grzegorz Jakiel
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  8 in total

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