Literature DB >> 24632348

Innate immunity in disease.

David E Elliott1, Sana S Siddique2, Joel V Weinstock3.   

Abstract

Cells can innately recognize generic products of viruses, bacteria, fungi, or injured tissue by engagement of pattern recognition receptors. Innate immune cells rapidly respond to this engagement to control commensals, thwart pathogens, and/or prompt repair. Insufficient or excessive activation of the innate immune response results in disease. This review focuses on pattern recognition receptors and cells of the innate immune system that are important for intestinal function. Our improving knowledge pertaining to this important aspect of our immune response is opening potential important new therapeutic opportunities for the treatment of disease.
Copyright © 2014 AGA Institute. Published by Elsevier Inc. All rights reserved.

Entities:  

Keywords:  Colitis; Gastroenterology; Innate Immunity; Mucosa

Mesh：

Substances：

Year:  2014        PMID： 24632348      PMCID： PMC4083246          DOI： 10.1016/j.cgh.2014.03.007

Source DB:  PubMed          Journal:  Clin Gastroenterol Hepatol        ISSN： 1542-3565            Impact factor:   11.382


  59 in total

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Journal:  Gut       Date:  2012-05-17       Impact factor: 23.059

2.  Reduced Paneth cell alpha-defensins in ileal Crohn's disease.

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Journal:  Proc Natl Acad Sci U S A       Date:  2005-12-05       Impact factor: 11.205

Review 3.  Contributions of dendritic cells and macrophages to intestinal homeostasis and immune defense.

Authors:  Julia Farache; Ehud Zigmond; Guy Shakhar; Steffen Jung
Journal:  Immunol Cell Biol       Date:  2013-02-12       Impact factor: 5.126

Review 4.  Paneth cells: maestros of the small intestinal crypts.

Authors:  Hans C Clevers; Charles L Bevins
Journal:  Annu Rev Physiol       Date:  2013       Impact factor: 19.318

Review 5.  Neutrophils in innate and adaptive immunity.

Authors:  Sébastien Jaillon; Maria Rosaria Galdiero; Davide Del Prete; Marco Antonio Cassatella; Cecilia Garlanda; Alberto Mantovani
Journal:  Semin Immunopathol       Date:  2013-04-04       Impact factor: 9.623

Review 6.  Primary immunodeficiencies of pattern recognition receptors.

Authors:  M G Netea; F L van de Veerdonk; J W M van der Meer
Journal:  J Intern Med       Date:  2012-09-12       Impact factor: 8.989

Review 7.  TLR-dependent T cell activation in autoimmunity.

Authors:  Kingston H G Mills
Journal:  Nat Rev Immunol       Date:  2011-11-18       Impact factor: 53.106

Review 8.  Neutrophil extracellular chromatin traps connect innate immune response to autoimmunity.

Authors:  Marko Radic; Tony N Marion
Journal:  Semin Immunopathol       Date:  2013-04-18       Impact factor: 9.623

9.  Evidence for a cross-talk between human neutrophils and Th17 cells.

Authors:  Martin Pelletier; Laura Maggi; Alessandra Micheletti; Elena Lazzeri; Nicola Tamassia; Claudio Costantini; Lorenzo Cosmi; Claudio Lunardi; Francesco Annunziato; Sergio Romagnani; Marco A Cassatella
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Journal:  J Exp Med       Date:  2004-10-11       Impact factor: 14.307
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  5 in total

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Authors:  S M Nashir Udden; Sumyya Waliullah; Melanie Harris; Hasan Zaki
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Review 2.  Survival of the Fittest: How Bacterial Pathogens Utilize Bile To Enhance Infection.

Authors:  Jeticia R Sistrunk; Kourtney P Nickerson; Rachael B Chanin; David A Rasko; Christina S Faherty
Journal:  Clin Microbiol Rev       Date:  2016-10       Impact factor: 26.132

3.  New understanding on the pathogenesis of acute arterial thrombosis.

Authors:  Le-Min Wang
Journal:  J Geriatr Cardiol       Date:  2015-05       Impact factor: 3.327

4.  Flavonoids Activation of the Transcription Factor Nrf2 as a Hypothesis Approach for the Prevention and Modulation of SARS-CoV-2 Infection Severity.

Authors:  Patricia Mendonca; Karam F A Soliman
Journal:  Antioxidants (Basel)       Date:  2020-07-24

5.  Molecular Diversification of the Seminal Fluid Proteome in a Recently Diverged Passerine Species Pair.

Authors:  Melissah Rowe; Emma Whittington; Kirill Borziak; Mark Ravinet; Fabrice Eroukhmanoff; Glenn-Peter Sætre; Steve Dorus
Journal:  Mol Biol Evol       Date:  2020-02-01       Impact factor: 16.240
  5 in total

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