M C Seck1, D Ndiaye2, K Diongue3, M Ndiaye1, A S Badiane1, D Sow4, K Sylla4, R Tine4, J L Ndiaye4, B Faye4, O Ndir1. 1. Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontostomatologie, université Cheikh Anta Diop, BP5005, Dakar, Sénégal; Laboratoire de parasitologie-mycologie, CHU Aristide le Dantec, BP16477, Dakar, Sénégal. 2. Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontostomatologie, université Cheikh Anta Diop, BP5005, Dakar, Sénégal; Laboratoire de parasitologie-mycologie, CHU Aristide le Dantec, BP16477, Dakar, Sénégal. Electronic address: daouda.ndiaye@ucad.edu.sn. 3. Laboratoire de parasitologie-mycologie, CHU Aristide le Dantec, BP16477, Dakar, Sénégal. 4. Service de parasitologie-mycologie, faculté de médecine, de pharmacie et d'odontostomatologie, université Cheikh Anta Diop, BP5005, Dakar, Sénégal.
Abstract
OBJECTIVE: Onychomycosis are a mycose of nail due to fungi. According to published data, they stands for half of all nail abnormalities. This survey was carried out to determine the frequency and the fungi involved in onychomycosis in Dakar. MATERIAL AND METHODS: This study was carried out at the laboratory of parasitology and mycology at Le Dantec Hospital, in Senegal from January 2008 to December 2012 and includes 507 patients. RESULTS: Onychomycosis were mycologically proved in 58.78% (298/507) of patients. Patient's age varies between 02 years to 82 years with a mean of 34.24 years. Women were more infected than men (sex-ratio was 2.38). Onychomycosis due to dermatophyte represented 37.92% (113/298) of patients and were essentially located on toes (60.71%). Distal and lateral subungual onychomycosis was the most frequent clinical form. Trichophyton rubrum and Trichophyton interdigitale were isolated respectively in 53.6% and 26.1% on toes. Yeasts represented 59.06% (176/298) of onychomycosis and were essentially located on fingernails (80.11%). Candida albicans represented 90.86% of isolated yeasts. Molds were isolated in nine cases (3.02%) and predominated in toenails. CONCLUSION: Among 507 patients with onychopathy, this study identified 298 cases of onychomycosis. T. rubrum was the main dermatophytes and was isolated on toenails whereas on fingernails C. albicans was more often observed.
OBJECTIVE:Onychomycosis are a mycose of nail due to fungi. According to published data, they stands for half of all nail abnormalities. This survey was carried out to determine the frequency and the fungi involved in onychomycosis in Dakar. MATERIAL AND METHODS: This study was carried out at the laboratory of parasitology and mycology at Le Dantec Hospital, in Senegal from January 2008 to December 2012 and includes 507 patients. RESULTS:Onychomycosis were mycologically proved in 58.78% (298/507) of patients. Patient's age varies between 02 years to 82 years with a mean of 34.24 years. Women were more infected than men (sex-ratio was 2.38). Onychomycosis due to dermatophyte represented 37.92% (113/298) of patients and were essentially located on toes (60.71%). Distal and lateral subungual onychomycosis was the most frequent clinical form. Trichophyton rubrum and Trichophyton interdigitale were isolated respectively in 53.6% and 26.1% on toes. Yeasts represented 59.06% (176/298) of onychomycosis and were essentially located on fingernails (80.11%). Candida albicans represented 90.86% of isolated yeasts. Molds were isolated in nine cases (3.02%) and predominated in toenails. CONCLUSION: Among 507 patients with onychopathy, this study identified 298 cases of onychomycosis. T. rubrum was the main dermatophytes and was isolated on toenails whereas on fingernails C. albicans was more often observed.
Authors: Aleph M S Souza; Renato C A Ribeiro; Gleyse K L O Pinheiro; Francisco I Pinheiro; Wógenes N Oliveira; Luanda B F C Souza; André L Silva; Lucas Amaral-Machado; Éverton N Alencar; Guilherme M Chaves; Eryvaldo S T Egito Journal: Pharmaceutics Date: 2021-05-24 Impact factor: 6.321