Literature DB >> 24631356

From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease.

Bhuminder Singh1, Robert J Coffey2.   

Abstract

Since its discovery in 1978 and cloning in 1984, transforming growth factor-alpha (TGF-α, TGFA) has been one of the most extensively studied EGF receptor (EGFR) ligands. In this review, we provide a historical perspective on TGFA-related studies, highlighting what we consider important advances related to its function in normal and disease states.
Copyright © 2014 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Autocrine singaling; Basolateral trafficking; EGFR, epidermal growth factor receptor; Ménétrier's disease; Polarized epithelial cells; TGFA, transforming growth factor alpha

Mesh：

Substances：

Year:  2014        PMID： 24631356      PMCID： PMC4105142          DOI： 10.1016/j.semcdb.2014.03.003

Source DB:  PubMed          Journal:  Semin Cell Dev Biol        ISSN： 1084-9521            Impact factor:   7.727


  125 in total

1.  Drosophila Cornichon acts as cargo receptor for ER export of the TGFalpha-like growth factor Gurken.

Authors:  Christian Bökel; Sajith Dass; Michaela Wilsch-Bräuninger; Siegfried Roth
Journal:  Development       Date:  2006-01-05       Impact factor: 6.868

2.  Overexpression of TGF alpha in transgenic mice: induction of epithelial hyperplasia, pancreatic metaplasia, and carcinoma of the breast.

Authors:  E P Sandgren; N C Luetteke; R D Palmiter; R L Brinster; D C Lee
Journal:  Cell       Date:  1990-06-15       Impact factor: 41.582

3.  Characterization of a human rhomboid homolog, p100hRho/RHBDF1, which interacts with TGF-alpha family ligands.

Authors:  Takatoshi Nakagawa; Annabel Guichard; Carolina Perez Castro; Yang Xiao; Michael Rizen; Hong-Zhong Zhang; Diane Hu; Anne Bang; Jill Helms; Ethan Bier; Rik Derynck
Journal:  Dev Dyn       Date:  2005-08       Impact factor: 3.780

4.  Identification of MAGI-3 as a transforming growth factor-alpha tail binding protein.

Authors:  Jeffrey L Franklin; Kenta Yoshiura; Peter J Dempsey; Galina Bogatcheva; Loice Jeyakumar; Katherine S Meise; R Scott Pearsall; David Threadgill; Robert J Coffey
Journal:  Exp Cell Res       Date:  2005-02-15       Impact factor: 3.905

5.  Inhibition of parietal cell H+ secretion by transforming growth factor alpha: a possible autocrine regulatory mechanism.

Authors:  J J Lewis; J R Goldenring; I M Modlin; R J Coffey
Journal:  Surgery       Date:  1990-08       Impact factor: 3.982

6.  Human keratinocytes and tumor-derived cell lines express alternatively spliced forms of transforming growth factor-alpha mRNA, encoding precursors lacking carboxyl-terminal valine residues.

Authors:  X Xu; J Liao; K E Creek; L Pirisi
Journal:  Oncogene       Date:  1999-09-30       Impact factor: 9.867

7.  Development of mammary hyperplasia and neoplasia in MMTV-TGF alpha transgenic mice.

Authors:  Y Matsui; S A Halter; J T Holt; B L Hogan; R J Coffey
Journal:  Cell       Date:  1990-06-15       Impact factor: 41.582

8.  Loss of TGF-beta type II receptor in fibroblasts promotes mammary carcinoma growth and invasion through upregulation of TGF-alpha-, MSP- and HGF-mediated signaling networks.

Authors:  Nikki Cheng; Neil A Bhowmick; Anna Chytil; Agnieszka E Gorksa; Kimberly A Brown; Rebecca Muraoka; Carlos L Arteaga; Eric G Neilson; Simon W Hayward; Harold L Moses
Journal:  Oncogene       Date:  2005-07-28       Impact factor: 9.867

9.  TGF alpha overexpression in transgenic mice induces liver neoplasia and abnormal development of the mammary gland and pancreas.

Authors:  C Jhappan; C Stahle; R N Harkins; N Fausto; G H Smith; G T Merlino
Journal:  Cell       Date:  1990-06-15       Impact factor: 41.582

10.  Cornichon regulates transport and secretion of TGFalpha-related proteins in metazoan cells.

Authors:  Carolina Perez Castro; Denise Piscopo; Takatoshi Nakagawa; Rik Derynck
Journal:  J Cell Sci       Date:  2007-07-15       Impact factor: 5.285
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  23 in total

1.  Induction of lateral lumens through disruption of a monoleucine-based basolateral-sorting motif in betacellulin.

Authors:  Bhuminder Singh; Galina Bogatcheva; Alina Starchenko; Justine Sinnaeve; Lynne A Lapierre; Janice A Williams; James R Goldenring; Robert J Coffey
Journal:  J Cell Sci       Date:  2015-08-13       Impact factor: 5.285

2.  Inflammation in the pathogenesis of lyme neuroborreliosis.

Authors:  Geeta Ramesh; Peter J Didier; John D England; Lenay Santana-Gould; Lara A Doyle-Meyers; Dale S Martin; Mary B Jacobs; Mario T Philipp
Journal:  Am J Pathol       Date:  2015-04-16       Impact factor: 4.307

3.  Multilayered proteomics reveals molecular switches dictating ligand-dependent EGFR trafficking.

Authors:  Chiara Francavilla; Moreno Papetti; Kristoffer T G Rigbolt; Anna-Kathrine Pedersen; Jon O Sigurdsson; Giuseppe Cazzamali; Gopal Karemore; Blagoy Blagoev; Jesper V Olsen
Journal:  Nat Struct Mol Biol       Date:  2016-05-02       Impact factor: 15.369

4.  Perturbed meibomian gland and tarsal plate morphogenesis by excess TGFα in eyelid stroma.

Authors:  Fei Dong; Chia-Yang Liu; Yong Yuan; Yujin Zhang; Wei Li; Mindy Call; Liyun Zhang; Yongxiong Chen; Zuguo Liu; Winston W Y Kao
Journal:  Dev Biol       Date:  2015-09-10       Impact factor: 3.582

5.  Targeted genotype analyses of GWAS-derived lean body mass and handgrip strength-associated single-nucleotide polymorphisms in elite master athletes.

Authors:  Hannah Crossland; Jessica Piasecki; Daniel McCormick; Bethan E Phillips; Daniel J Wilkinson; Kenneth Smith; Jamie S McPhee; Mathew Piasecki; Philip J Atherton
Journal:  Am J Physiol Regul Integr Comp Physiol       Date:  2020-06-24       Impact factor: 3.619

6.  Targeting cartilage EGFR pathway for osteoarthritis treatment.

Authors:  Yulong Wei; Lijun Luo; Tao Gui; Feifan Yu; Lesan Yan; Lutian Yao; Leilei Zhong; Wei Yu; Biao Han; Jay M Patel; Jessica F Liu; Frank Beier; Lawrence Scott Levin; Charles Nelson; Zengwu Shao; Lin Han; Robert L Mauck; Andrew Tsourkas; Jaimo Ahn; Zhiliang Cheng; Ling Qin
Journal:  Sci Transl Med       Date:  2021-01-13       Impact factor: 17.956

7.  Accelerated wound closure in vitro by fibroblasts from a subgroup of cleft lip/palate patients: role of transforming growth factor-α.

Authors:  Joël Beyeler; Isabelle Schnyder; Christos Katsaros; Matthias Chiquet
Journal:  PLoS One       Date:  2014-10-31       Impact factor: 3.240

Review 8.  The angiogenic asset of soft tissue sarcomas: a new tool to discover new therapeutic targets.

Authors:  Laura Rocchi; Stefano Caraffi; Roberto Perris; Domenica Mangieri
Journal:  Biosci Rep       Date:  2014-11-04       Impact factor: 3.840

9.  Associations Between TGFA/TGFB3/MSX1 Gene Polymorphisms and Congenital Non-Syndromic Hearing Impairment in a Chinese Population.

Authors:  Jihong Du; Jianhua Deng
Journal:  Med Sci Monit       Date:  2016-06-29

10.  Rhomboid intramembrane protease RHBDL4 triggers ER-export and non-canonical secretion of membrane-anchored TGFα.

Authors:  Lina Wunderle; Julia D Knopf; Nathalie Kühnle; Aymeric Morlé; Beate Hehn; Colin Adrain; Kvido Strisovsky; Matthew Freeman; Marius K Lemberg
Journal:  Sci Rep       Date:  2016-06-06       Impact factor: 4.379
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