| Literature DB >> 24630714 |
Lisa Vincenz1, F Ulrich Hartl2.
Abstract
The hexosamine biosynthetic pathway (HBP) generates metabolites for protein N- and O-glycosylation. Wang et al. and Denzel et al. report a hitherto unknown link between the HBP and stress in the endoplasmic reticulum. These studies establish the HBP as a critical component of the cellular machinery of protein homeostasis.Entities:
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Year: 2014 PMID: 24630714 DOI: 10.1016/j.cell.2014.02.035
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582